Quantitative positron emission tomography (PET) brain studies often require that the input
function be measured, typically via arterial cannulation. Image-derived input function (IDIF) …

Background The need for arterial blood data in quantitative PET research limits the wider
usability of this imaging method in clinical research settings. Image-derived input function …

Purpose To assess the robustness of a previously introduced method to obtain accurate
image-derived input functions (IDIF) for three other tracers. Methods Dynamic PET and …

Pharmacokinetic modelling with arterial sampling is the gold standard for analysing dynamic
PET data of the brain. However, the invasive character of arterial sampling prevents its …

Measurement of arterial input function is a restrictive aspect for quantitative 18F-FDG PET
studies in rodents because of their small total blood volume and the related difficulties in …

15O-H2O PET imaging is an accurate method to measure cerebral blood flow (CBF) but it
requires an arterial input function (AIF). Historically, image-derived AIF estimation suffers …

Absolute quantification of PET brain imaging requires the measurement of an arterial input
function (AIF), typically obtained invasively via an arterial cannulation. We present an …

Kinetic analysis of 18F-fluorodeoxyglucose positron emission tomography data requires an
accurate knowledge the arterial input function. The gold standard method to measure the …

Extraction of arterial input functions from dynamic brain scans may obviate the need for
arterial sampling and would increase the clinical applicability of quantitative PET studies …

Purpose Despite current advances in PET/CT systems, blood sampling still remains the
standard method to obtain the radiotracer input function for tracer kinetic modelling. The …