[HTML][HTML] Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials
Z Niu, R Jin, Y Zhang, H Li - Signal Transduction and Targeted Therapy, 2022 - nature.com
Lung cancer is the leading cause of cancer-related death across the world. Unlike lung
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …
[PDF][PDF] Squamous cell lung cancer: Current landscape and future therapeutic options
Squamous cell lung cancers (lung squamous cell carcinomas [LUSCs]) are associated with
high mortality and a lack of therapies specific to this disease. Although recurrent molecular …
high mortality and a lack of therapies specific to this disease. Although recurrent molecular …
Squamous-cell carcinomas of the lung: emerging biology, controversies, and the promise of targeted therapy
Squamous-cell carcinomas of the lung (SQCLCs) are defined by unique clinicopathological
and molecular characteristics that have evolved substantially over time. Historically, these …
and molecular characteristics that have evolved substantially over time. Historically, these …
Squamous cell lung cancer: from tumor genomics to cancer therapeutics
DR Gandara, PS Hammerman, ML Sos, PN Lara Jr… - Clinical cancer …, 2015 - AACR
Squamous cell lung cancer (SCC) represents an area of unmet need in lung cancer
research. For the past several years, therapeutic progress in SCC has lagged behind the …
research. For the past several years, therapeutic progress in SCC has lagged behind the …
[HTML][HTML] Treatment of advanced squamous cell carcinoma of the lung: a review
BA Derman, KF Mileham, PD Bonomi… - … lung cancer research, 2015 - ncbi.nlm.nih.gov
Lung cancer remains the single deadliest cancer both in the US and worldwide. The great
majority of squamous cell carcinoma (SCC) is attributed to cigarette smoking, which …
majority of squamous cell carcinoma (SCC) is attributed to cigarette smoking, which …
Pathogenesis of lung cancer signalling pathways: roadmap for therapies
E Brambilla, A Gazdar - European Respiratory Journal, 2009 - Eur Respiratory Soc
Lung cancer is the major cancer killer worldwide, and 5-yr survival is extremely poor (≤
15%), accentuating the need for more effective therapeutic strategies. Significant advances …
15%), accentuating the need for more effective therapeutic strategies. Significant advances …
Non-small-cell lung cancers: a heterogeneous set of diseases
Z Chen, CM Fillmore, PS Hammerman, CF Kim… - Nature Reviews …, 2014 - nature.com
Non-small-cell lung cancers (NSCLCs), the most common lung cancers, are known to have
diverse pathological features. During the past decade, in-depth analyses of lung cancer …
diverse pathological features. During the past decade, in-depth analyses of lung cancer …
[HTML][HTML] Molecular pathways and therapeutic targets in lung cancer
E Shtivelman, T Hensing, GR Simon, PA Dennis… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Lung cancer is still the leading cause of cancer death worldwide. Both histologically and
molecularly lung cancer is heterogeneous. This review summarizes the current knowledge …
molecularly lung cancer is heterogeneous. This review summarizes the current knowledge …
[HTML][HTML] Immunotherapy and targeted therapy for lung cancer: Current status and future perspectives
Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A
large number of patients are diagnosed with lung cancer at the later stages of the disease …
large number of patients are diagnosed with lung cancer at the later stages of the disease …
[HTML][HTML] Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function
Background Lung squamous cell carcinoma (LUSC) accounts for 20–30% of non-small cell
lung cancers (NSCLCs). There are limited treatment strategies for LUSC in part due to our …
lung cancers (NSCLCs). There are limited treatment strategies for LUSC in part due to our …
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