Bacteremic sepsis leads to higher mortality when adjusting for confounders with propensity score matching

L Mellhammar, F Kahn, C Whitlow, T Kander… - Scientific reports, 2021 - nature.com
One can falsely assume that it is well known that bacteremia is associated with higher
mortality in sepsis. Only a handful of studies specifically focus on the comparison of culture …

Reappraisal with meta-analysis of bacteremia, endotoxemia, and mortality in gram-negative sepsis

JC Hurley - Journal of clinical microbiology, 1995 - Am Soc Microbiol
Among patients with suspected sepsis, endotoxemia is variably present in association with
gram-negative bacteremia. A total of 738 patients with suspected sepsis from 11 studies …

Culture-negative and culture-positive sepsis: a comparison of characteristics and outcomes

MJG Sigakis, E Jewell, MD Maile, SK Cinti… - Anesthesia & …, 2019 - journals.lww.com
BACKGROUND: The primary objective of this study was to compare the characteristics of
culture-positive and culture-negative status in septic patients. We also determined whether …

Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis

A Komori, T Abe, S Kushimoto, H Ogura, A Shiraishi… - Scientific reports, 2020 - nature.com
The clinical implications of bacteremia among septic patients remain unclear, although a
vast amount of data have been accumulated on sepsis. We aimed to compare the clinical …

Primary bacteraemia is associated with a higher mortality risk compared with pulmonary and intra-abdominal infections in patients with sepsis: a prospective …

A Mansur, Y Klee, AF Popov, J Erlenwein, M Ghadimi… - BMJ open, 2015 - bmjopen.bmj.com
Objective To investigate whether common infection foci (pulmonary, intra-abdominal and
primary bacteraemia) are associated with variations in mortality risk in patients with sepsis …

Neither blood culture positivity nor time to positivity is associated with mortality among patients presenting with severe manifestations of sepsis: the FABLED cohort …

K Paquette, D Sweet, R Stenstrom… - Open Forum …, 2021 - academic.oup.com
Background Sepsis is a leading cause of morbidity, mortality, and health care costs
worldwide. Methods We conducted a multicenter, prospective cohort study evaluating the …

Characterization of pathogenic sepsis etiologies and patient profiles: a novel approach to triage and treatment

HH Dolin, TJ Papadimos, X Chen… - Microbiology …, 2019 - journals.sagepub.com
Pathogenic sepsis is not a monolithic condition. Three major types of sepsis exist within this
category: bacterial, viral, and fungal, each with its own mechanism of action. While similar in …

Comparison of clinical characteristics and outcomes between positive and negative blood culture septic patients: a retrospective cohort study

L Yang, Y Lin, J Wang, J Song, B Wei… - Infection and Drug …, 2021 - Taylor & Francis
Background Few studies have studied the relationship between blood culture and mortality
in sepsis patients. The aim of this study was to compare the characteristics and outcomes of …

Mortality in intensive care: the impact of bacteremia and the utility of systemic inflammatory response syndrome

D Brooks, A Smith, D Young, R Fulton… - American journal of …, 2016 - Elsevier
Background The purpose of this study was to determine the impact of bacteremia on
intensive care unit (ICU) mortality and to develop a bacteremia prediction tool using …

Sepsis in standard care: patients' characteristics, effectiveness of antimicrobial therapy and patient outcome—a cohort study

F Ratzinger, K Eichbichler, M Schuardt, I Tsirkinidou… - Infection, 2015 - Springer
Purpose Fast diagnosis and initiation of appropriate antibiotic therapy is pivotal for the
survival of sepsis patients. However, most studies on suspected sepsis patients are …