Asymptomatic hyperuricaemia in chronic kidney disease: mechanisms and clinical implications
Asymptomatic hyperuricaemia (HU) is considered a pathogenic factor in multiple disease
contexts, but a causative role is only proven for the crystalline form of uric acid in gouty …
contexts, but a causative role is only proven for the crystalline form of uric acid in gouty …
[HTML][HTML] Pathophysiology of hyperuricemia and its clinical significance–a narrative review
M Skoczyńska, M Chowaniec, A Szymczak… - …, 2020 - ncbi.nlm.nih.gov
Hyperuricemia, ie increased serum uric acid (UA) concentration, is a common problem in
clinical practice. While there are clear guidelines concerning management of symptomatic …
clinical practice. While there are clear guidelines concerning management of symptomatic …
[HTML][HTML] Uric acid and chronic kidney disease: still more to do
Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney
disease (CKD), respectively. Despite the common association, the role of uric acid in the …
disease (CKD), respectively. Despite the common association, the role of uric acid in the …
Hyperuricemia and progression of chronic kidney disease: a review from physiology and pathogenesis to the role of urate-lowering therapy
The relationship between hyperuricemia, gout, and renal disease has been investigated for
several years. From the beginning, kidney disease has been considered a complication of …
several years. From the beginning, kidney disease has been considered a complication of …
Asymptomatic hyperuricaemia: a silent activator of the innate immune system
Asymptomatic hyperuricaemia affects~ 20% of the general population in the USA, with
variable rates in other countries. Historically, asymptomatic hyperuricaemia was considered …
variable rates in other countries. Historically, asymptomatic hyperuricaemia was considered …
Hyperuricemia, the kidneys, and the spectrum of associated diseases: a narrative review
DI Jalal - Current medical research and opinion, 2016 - Taylor & Francis
Hyperuricemia (elevated serum uric acid) is prevalent, and an important mediator of gout, an
increasingly common condition. In addition, hyperuricemia is associated with metabolic …
increasingly common condition. In addition, hyperuricemia is associated with metabolic …
Effects of uric acid dysregulation on the kidney
LV Dissanayake, DR Spires… - American Journal …, 2020 - journals.physiology.org
Recently, research has redirected its interests in uric acid (UA) from gout, an inflammatory
disease in joints, to groups of closely interrelated pathologies associated with …
disease in joints, to groups of closely interrelated pathologies associated with …
Hyperuricemia, hypertension, and chronic kidney disease: an emerging association
Uric acid is a product of purine metabolism and has been linked to gout and kidney calculi.
Chronic kidney disease (CKD) and hypertension (HTN) are two major public health …
Chronic kidney disease (CKD) and hypertension (HTN) are two major public health …
Advanced kidney failure and hyperuricemia
M Murea - Advances in chronic kidney disease, 2012 - Elsevier
Metabolic end products accumulate in kidney failure, including uric acid (UA), a terminal
product of purine catabolism. Hyperuricemia (HUA) can cause gout and has been …
product of purine catabolism. Hyperuricemia (HUA) can cause gout and has been …
Why focus on uric acid?
RJ Johnson - Current medical research and opinion, 2015 - Taylor & Francis
In gouty patients, urate lowering therapies (ULTs) are recommended to bring serum uric acid
(SUA) levels below 6.0 mg/dL, with the aim of dissolving urate depositions, thereby reducing …
(SUA) levels below 6.0 mg/dL, with the aim of dissolving urate depositions, thereby reducing …
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