Rationale Deficient response inhibition is a prominent feature of many pathological
conditions characterised by impulsive and compulsive behaviour. Clinically effective doses …

Rationale Impulsivity is associated with a number of psychiatric disorders, most notably
attention deficit/hyperactivity disorder (ADHD). Drugs that augment catecholamine function …

Defining the neural and neurochemical substrates of response inhibition is of crucial
importance for the study and treatment of pathologies characterized by impulsivity such as …

High levels of impulsive behaviours are a clinically significant symptom in a range of
psychiatric disorders, such as attention deficit hyperactivity disorder, bipolar disorder …

Animal models are making an increasing contribution to our understanding of the
psychology and brain mechanisms underlying behavioral inhibition and impulsivity. The aim …

Impulsive acts and decisions are a part of everyday normal behavior. However, in its
pathological forms, impulsivity can be a debilitating disorder often associated with a number …

Rationale The stop-signal paradigm measures the ability to stop a motor response after its
execution has been initiated. Impairments in inhibiting inappropriate behavior and …

Rationale High levels of impulsivity are a core symptom of psychiatric disorders such as
ADHD, mania, personality disorders and drug addiction. The effectiveness of drugs targeting …

Impulsivity is a core deficit of a number of neuropsychiatric disorders including attention-
deficit hyperactivity disorder (ADHD), anti-social conduct disorder and drug addiction …

Previous studies have shown that drugs which block the reuptake of catecholamine
neurotransmitters improve impulse control in diseases such as attention deficit hyperactivity …