Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo
Although much is known about the biochemical regulation of glycolytic enzymes, less is
understood about how they are organized inside cells. We systematically examine the …
understood about how they are organized inside cells. We systematically examine the …
The glycolytic enzyme phosphofructokinase-1 assembles into filaments
Despite abundant knowledge of the regulation and biochemistry of glycolytic enzymes, we
have limited understanding on how they are spatially organized in the cell. Emerging …
have limited understanding on how they are spatially organized in the cell. Emerging …
A simulation study of mammalian phosphofructokinase
D Garfinkel - Journal of Biological Chemistry, 1966 - ASBMB
A computer model of the mammalian muscle phosphofructokinase system (with associated
chemical reactions) has been constructed in which 22 differential equations represent 22 …
chemical reactions) has been constructed in which 22 differential equations represent 22 …
Covalent modification of phosphofructokinase by phosphorylation—dephosphorylation
HD SÖLING, IA BRAND - Current topics in cellular regulation, 1981 - Elsevier
Publisher Summary This chapter reviews the process of covalent modification of
phosphofructokinase by phosphorylation–dephosphorylation. The desensitizing factor had …
phosphofructokinase by phosphorylation–dephosphorylation. The desensitizing factor had …
Yeast phosphofructokinase-1 subunit Pfk2p is necessary for pH homeostasis and glucose-dependent vacuolar ATPase reassembly
V-ATPases are conserved ATP-driven proton pumps that acidify organelles. Yeast V-
ATPase assembly and activity are glucose-dependent. Glucose depletion causes V-ATPase …
ATPase assembly and activity are glucose-dependent. Glucose depletion causes V-ATPase …
Subunit interaction of rabbit muscle phosphofructokinase: effects of purification procedures
MA Luther, LK Hesterberg, JC Lee - Biochemistry, 1985 - ACS Publications
Structural, physical, and kinetic properties of rabbit muscle phosphofructokinase (PFK)
purified by three different procedures were monitored in order to determine the effect of …
purified by three different procedures were monitored in order to determine the effect of …
Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations
Abstract Phosphofructokinase-1 (PFK1), the 'gatekeeper'of glycolysis, catalyses the
committed step of the glycolytic pathway by converting fructose-6-phosphate to fructose-1, 6 …
committed step of the glycolytic pathway by converting fructose-6-phosphate to fructose-1, 6 …
The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle
K Banaszak, I Mechin, G Obmolova, M Oldham… - Journal of Molecular …, 2011 - Elsevier
Phosphofructokinase 1 (PFK) is a multisubunit allosteric enzyme that catalyzes the principal
regulatory step in glycolysis—the phosphorylation of fructose 6-phosphate to fructose 1, 6 …
regulatory step in glycolysis—the phosphorylation of fructose 6-phosphate to fructose 1, 6 …
Evolution of phosphofructokinase—gene duplication and creation of new effector sites
RA Poorman, A Randolph, RG Kemp, RL Heinrikson - Nature, 1984 - nature.com
Abstract Phosphofructokinases (PFK; EC 2.7. 1.11) are tetrameric enzymes that have a key
role in the regulation of glycolysls1; as such, they are subject to allosteric activation and …
role in the regulation of glycolysls1; as such, they are subject to allosteric activation and …
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1
A Herrero-Mendez, A Almeida, E Fernández… - Nature cell …, 2009 - nature.com
Neurons are known to have a lower glycolytic rate than astrocytes and when stressed they
are unable to upregulate glycolysis because of low Pfkfb3 (6-phosphofructo-2 …
are unable to upregulate glycolysis because of low Pfkfb3 (6-phosphofructo-2 …