Astaxanthin anticancer effects are mediated through multiple molecular mechanisms: A systematic review
During the latest decades, the interest on the effectiveness of natural compounds and their
impact on human health constantly increased, especially on those demonstrating to be …
impact on human health constantly increased, especially on those demonstrating to be …
[HTML][HTML] Multiple mechanisms of anti-cancer effects exerted by astaxanthin
L Zhang, H Wang - Marine drugs, 2015 - mdpi.com
Astaxanthin (ATX) is a xanthophyll carotenoid which has been approved by the United
States Food and Drug Administration (USFDA) as food colorant in animal and fish feed. It is …
States Food and Drug Administration (USFDA) as food colorant in animal and fish feed. It is …
Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials
A Donoso, J González-Durán, AA Muñoz… - Pharmacological …, 2021 - Elsevier
Astaxanthin is a natural C40 carotenoid with numerous reported biological functions, most of
them associated with its antioxidant and anti-inflammatory activity, standing out from other …
them associated with its antioxidant and anti-inflammatory activity, standing out from other …
[HTML][HTML] Anti-oxidant and anti-inflammatory effects of astaxanthin on gastrointestinal diseases
J Lee, MH Kim, H Kim - International journal of molecular sciences, 2022 - mdpi.com
A moderate amount of reactive oxygen species (ROS) is produced under normal conditions,
where they play an important role in cell signaling and are involved in many aspects of the …
where they play an important role in cell signaling and are involved in many aspects of the …
Zeaxanthin induces apoptosis via ROS-regulated MAPK and AKT signaling pathway in human gastric cancer cells
YN Sheng, YH Luo, SB Liu, WT Xu, Y Zhang… - OncoTargets and …, 2020 - Taylor & Francis
Background Zeaxanthin, a carotenoid commonly found in plants, has a variety of biological
functions including anti-cancer activity. Purpose This study aimed to investigate the potential …
functions including anti-cancer activity. Purpose This study aimed to investigate the potential …
Astaxanthin inhibits NF-κB and Wnt/β-catenin signaling pathways via inactivation of Erk/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral …
K Kavitha, J Kowshik, TKK Kishore, AB Baba… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Background The oncogenic transcription factors NF-κB and β-catenin, constitutively
activated by upstream serine/threonine kinases control several cellular processes implicated …
activated by upstream serine/threonine kinases control several cellular processes implicated …
[HTML][HTML] Astaxanthin inhibits JAK/STAT-3 signaling to abrogate cell proliferation, invasion and angiogenesis in a hamster model of oral cancer
Identifying agents that inhibit STAT-3, a cytosolic transcription factor involved in the
activation of various genes implicated in tumour progression is a promising strategy for …
activation of various genes implicated in tumour progression is a promising strategy for …
Astaxanthin induces apoptosis and increases activity of antioxidant enzymes in LS-180 cells
M Hormozi, S Ghoreishi… - … cells, nanomedicine, and …, 2019 - Taylor & Francis
Astaxanthin, a Xanthophyll carotenoid, has strong antioxidant properties. Some studies have
shown the effectiveness of this compound on the prevention and treatment of cancer …
shown the effectiveness of this compound on the prevention and treatment of cancer …
Astaxanthin: a review of its chemistry and applications
I Higuera-Ciapara, L Felix-Valenzuela… - Critical reviews in …, 2006 - Taylor & Francis
Astaxanthin is a carotenoid widely used in salmonid and crustacean aquaculture to provide
the pink color characteristic of that species. This application has been well documented for …
the pink color characteristic of that species. This application has been well documented for …
[HTML][HTML] Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases
Z Kohandel, T Farkhondeh, M Aschner… - Biomedicine & …, 2022 - Elsevier
Astaxanthin (AST) is a red pigmented carotenoid with significant antioxidant, anti-
inflammatory, anti-proliferative, and anti-apoptotic properties. In this study, we summarize …
inflammatory, anti-proliferative, and anti-apoptotic properties. In this study, we summarize …