Vancomycin (Van) is a key antibiotic of choice for the treatment of systemic methicillin
resistant Staphylococcus aureus (MRSA) infections. However, due to its poor membrane …

The rapid emergence of drug resistance continues to outpace the development of new
antibiotics in the treatment of infectious diseases. Conventional therapy is currently limited …

An urgent demand exists for the development of novel delivery systems that efficiently
transport antibacterial agents across cellular membranes for the eradication of intracellular …

Abstract Treatment of polymicrobial infections requires combination therapy with drugs that
have different antimicrobial spectra and possibly work in synergy. However, the different …

The abuse of antibiotics has led to the emergence of antibiotic resistant bacteria and high
threats to human health. The search for safe and effective alternatives to traditional …

Mesoporous silica nanoparticles (MSNs) exhibit unique drug delivery properties and are
thus considered as promising candidates for next generation nano-medicines. In particular …

Mesoporous silica nanoparticles (MSNs) have been explored extensively as solid supports
for proteins in biological and medical applications. Small (< 200 nm) MSNs with ordered …

Nanotechnology is a fast-growing area, involving the fabrication and use of nano-sized
materials and devices. Nanocomposite materials play a number of important roles in modern …

The ability of bacteria to form biofilms hinders any conventional treatment for chronic
infections and has serious socio-economic implications. For this purpose, a nanocarrier …

Novel multi-responsive drug delivery vehicles (CDs/PNVCL@ HMSNs) were prepared by
grafting amino-terminated poly (N-vinyl caprolactam)(PNVCL-NH 2) and amino-rich carbon …