Nebulized 5% or 3% hypertonic or 0.9% saline for treating acute bronchiolitis in infants

K Al-Ansari, M Sakran, BL Davidson, R El Sayyed… - The Journal of …, 2010 - Elsevier
OBJECTIVE: To compare the efficacy and safety of 5%, 3%, and 0.9% saline solution for
treating acute bronchiolitis in the prehospital setting. STUDY DESIGN: This was a double …

Nebulized hypertonic saline for bronchiolitis in the emergency department: a randomized clinical trial

TA Florin, KN Shaw, M Kittick, S Yakscoe… - JAMA pediatrics, 2014 - jamanetwork.com
Importance Acute bronchiolitis is the most frequent lower respiratory tract infection in infants,
yet there are no effective therapies available. Current evidence is unclear about the role of …

Effect of nebulized hypertonic saline treatment in emergency departments on the hospitalization rate for acute bronchiolitis: a randomized clinical trial

F Angoulvant, X Bellêttre, K Milcent, JP Teglas… - JAMA …, 2017 - jamanetwork.com
Importance Acute bronchiolitis is the leading cause of hospitalization among infants.
Previous studies, underpowered to examine hospital admission, have found a limited benefit …

Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial

S Wu, C Baker, ME Lang, SM Schrager, FF Liley… - JAMA …, 2014 - jamanetwork.com
Importance Bronchiolitis is one of the most common and costly respiratory diseases in
infants and young children. Previous studies have shown a potential benefit of nebulized …

Nebulized hypertonic saline without adjunctive bronchodilators for children with bronchiolitis

S Ralston, V Hill, M Martinez - Pediatrics, 2010 - publications.aap.org
OBJECTIVE: The goal was to determine an adverse event rate for nebulized hypertonic
saline solution administered without adjunctive bronchodilators for infants with bronchiolitis …

Hypertonic (3%) saline Vs 0.9% saline nebulization for acute viral bronchiolitis: A randomized controlled trial

BS Sharma, MK Gupta, SP Rafik - Indian pediatrics, 2013 - Springer
Objective To compare the length of hospital stay (primary) and improvement in clinical
severity scores (secondary) among children with bronchiolitis nebulized with 3% hypertonic …

A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department

S Grewal, S Ali, DW McConnell… - … of pediatrics & …, 2009 - jamanetwork.com
Objective To determine whether nebulized 3% hypertonic saline with epinephrine is more
effective than nebulized 0.9% saline with epinephrine in the treatment of bronchiolitis in the …

A randomized trial of nebulized 3% hypertonic saline with salbutamol in the treatment of acute bronchiolitis in hospitalized infants

P Flores, AL Mendes, AS Neto - Pediatric pulmonology, 2016 - Wiley Online Library
Objective Acute bronchiolitis is a common disorder of infants that often results in
hospitalization. Apart from supportive care, no therapy has been shown to influence the …

Nebulized hypertonic saline for acute bronchiolitis: a systematic review

L Zhang, RA Mendoza-Sassi, TP Klassen… - …, 2015 - publications.aap.org
BACKGROUND AND OBJECTIVE: The mainstay of treatment for acute bronchiolitis remains
supportive care. The objective of this study was to assess the efficacy and safety of …

Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants

BA Kuzik, SA Al Qadhi, S Kent, MP Flavin… - The Journal of …, 2007 - Elsevier
OBJECTIVE: To investigate the use of nebulized 3% hypertonic saline (HS) for treating viral
bronchiolitis in moderately ill hospitalized infants by a prospective, randomized, double …