Implications on clinical scenario of gold nanoparticle radiosensitization in regards to photon energy, nanoparticle size, concentration and location
E Lechtman, N Chattopadhyay, Z Cai… - Physics in Medicine …, 2011 - iopscience.iop.org
Gold nanoparticle (AuNP) radiosensitization represents a novel approach to enhance the
effectiveness of ionizing radiation. Its efficiency varies widely with photon source energy and …
effectiveness of ionizing radiation. Its efficiency varies widely with photon source energy and …
A Monte Carlo-based model of gold nanoparticle radiosensitization accounting for increased radiobiological effectiveness
E Lechtman, S Mashouf… - Physics in Medicine …, 2013 - iopscience.iop.org
Radiosensitization using gold nanoparticles (AuNPs) has been shown to vary widely with
cell line, irradiation energy, AuNP size, concentration and intracellular localization. We …
cell line, irradiation energy, AuNP size, concentration and intracellular localization. We …
Gold nanoparticles as radiation sensitizers in cancer therapy
DB Chithrani, S Jelveh, F Jalali… - Radiation …, 2010 - meridian.allenpress.com
Among other nanoparticle systems, gold nanoparticles have been explored as
radiosensitizers. While most of the research in this area has focused on either gold …
radiosensitizers. While most of the research in this area has focused on either gold …
Biological mechanisms of gold nanoparticle radiosensitization
S Rosa, C Connolly, G Schettino, KT Butterworth… - Cancer …, 2017 - Springer
There has been growing interest in the use of nanomaterials for a range of biomedical
applications over the last number of years. In particular, gold nanoparticles (GNPs) possess …
applications over the last number of years. In particular, gold nanoparticles (GNPs) possess …
Radiosensitization by gold nanoparticles
B Jeremic, AR Aguerri, N Filipovic - Clinical and Translational Oncology, 2013 - Springer
Recent years brought increasing use of gold nano particles (GNP) as a model platform for
interaction of irradiation and GNPs aiming radiosensitization. Endocytosis seems to be one …
interaction of irradiation and GNPs aiming radiosensitization. Endocytosis seems to be one …
Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?
L Cui, S Her, GR Borst, RG Bristow, DA Jaffray… - Radiotherapy and …, 2017 - Elsevier
The utilization of gold nanoparticles (AuNPs) as radiosensitizers has shown great promise in
pre-clinical research. In the current review, the physical, chemical, and biological pathways …
pre-clinical research. In the current review, the physical, chemical, and biological pathways …
Estimation of tumour dose enhancement due to gold nanoparticles during typical radiation treatments: a preliminary Monte Carlo study
SH Cho - Physics in Medicine & Biology, 2005 - iopscience.iop.org
A recent mice study demonstrated that gold nanoparticles could be safely administered and
used to enhance the tumour dose during radiation therapy. The use of gold nanoparticles …
used to enhance the tumour dose during radiation therapy. The use of gold nanoparticles …
Dependence of gold nanoparticle radiosensitization on cell geometry
The radiosensitization effect of gold nanoparticles (GNPs) has been demonstrated both in
vitro and in vivo in radiation therapy. The purpose of this study was to systematically assess …
vitro and in vivo in radiation therapy. The purpose of this study was to systematically assess …
Roadmap to clinical use of gold nanoparticles for radiation sensitization
The past decade has seen a dramatic increase in interest in the use of gold nanoparticles
(GNPs) as radiation sensitizers for radiation therapy. This interest was initially driven by their …
(GNPs) as radiation sensitizers for radiation therapy. This interest was initially driven by their …
Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles
JA Coulter, S Jain, KT Butterworth… - International journal …, 2012 - Taylor & Francis
Background This follow-up study aims to determine the physical parameters which govern
the differential radiosensitization capacity of two tumor cell lines and one immortalized …
the differential radiosensitization capacity of two tumor cell lines and one immortalized …
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