The good, the bad, and the ugly of metals as antimicrobials

RJ Turner - Biometals, 2024 - Springer
We are now moving into the antimicrobial resistance (AMR) era where more antibiotic
resistant bacteria are now the majority, a problem brought on by both misuse and over use …

Metal Based Antimicrobials: Uses and Challenges

DA Salazar-Alemán, RJ Turner - Microbial Metabolism of Metals and …, 2022 - Springer
In this antimicrobial resistance era, where resistance to most antibiotics is commonplace,
metals and metalloid based antimicrobials (MBA) have emerged as an alternative to treat …

The potential of metals in combating bacterial pathogens

N Gugala, RJ Turner - Biomedical applications of metals, 2018 - Springer
The progression of antimicrobial resistance and the presence of microbial biofilms pose
serious threats, which have prompted the development of novel antimicrobials such as …

Metals to combat antimicrobial resistance

A Frei, AD Verderosa, AG Elliott, J Zuegg… - Nature Reviews …, 2023 - nature.com
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens

A Evans, KA Kavanagh - Journal of Medical Microbiology, 2021 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the greatest global health challenges of modern
times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of …

Antimicrobial activity of metals: mechanisms, molecular targets and applications

JA Lemire, JJ Harrison, RJ Turner - Nature Reviews Microbiology, 2013 - nature.com
Metals have been used as antimicrobial agents since antiquity, but throughout most of
history their modes of action have remained unclear. Recent studies indicate that different …

Metal-based antimicrobials

NK Monych, N Gugala, RJ Turner - 2019 - books.rsc.org
The introduction of antibiotics originated from the discovery of penicillin by Sir Alexander
Fleming in 1928, thus fueling a new medical era. 1 Antibiotics were once regarded as …

[HTML][HTML] Recent advances in the development of metal complexes as antibacterial agents with metal-specific modes of action

JE Waters, L Stevens-Cullinane, L Siebenmann… - Current Opinion in …, 2023 - Elsevier
The mounting burden of antimicrobial resistance (AMR) is one of the most concerning
threats to public health worldwide. With low economic incentives and a dwindling supply of …

Is silver the ultimate antimicrobial bullet?

RJ Turner - Antibiotics, 2018 - mdpi.com
The use of metal compounds as antimicrobial agents has been around since antiquity, only
to be replaced by the introduction of organic antibiotics and antiseptics in the mid-20th …

[PDF][PDF] Metal complexes as prospective antibacterial agents

JA Obaleye, AC Tella… - A Search for Antibacterial …, 2012 - researchgate.net
Ninety elements occur naturally on earth. Out of these, nine are radioactive and among the
remaining eighty one that could support life, sixty one are metals. Our bodies are 3% metal …