Potential involvement of the extracranial venous system in central nervous system disorders and aging

R Zivadinov, CP Chung - BMC medicine, 2013 - Springer
Background The role of the extracranial venous system in the pathology of central nervous
system (CNS) disorders and aging is largely unknown. It is acknowledged that the …

Is there a link between the extracranial venous system and central nervous system pathology?

R Zivadinov - BMC medicine, 2013 - Springer
The extracranial venous system is complex and variable between individuals. Until recently,
these variations were acknowledged as developmental variants and were not considered …

What went wrong? The flawed concept of cerebrospinal venous insufficiency

JM Valdueza, F Doepp, SJ Schreiber… - Journal of Cerebral …, 2013 - journals.sagepub.com
In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the
central nervous system is associated with multiple sclerosis (MS), coining the term of chronic …

The role of noninvasive and invasive diagnostic imaging techniques for detection of extra-cranial venous system anomalies and developmental variants

K Dolic, AH Siddiqui, Y Karmon, K Marr, R Zivadinov - BMC medicine, 2013 - Springer
The extra-cranial venous system is complex and not well studied in comparison to the
peripheral venous system. A newly proposed vascular condition, named chronic …

[HTML][HTML] A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency

P Zamboni, R Galeotti, E Menegatti… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
combined stenoses of the principal pathways of extracranial venous drainage, including the …

Chronic cerebrospinal venous insufficiency and multiple sclerosis

O Khan, M Filippi, MS Freedman, F Barkhof… - Annals of …, 2010 - Wiley Online Library
A chronic state of impaired venous drainage from the central nervous system, termed
chronic cerebrospinal venous insufficiency (CCSVI), is claimed to be a pathologic …

Cerebral venous disorders: Diagnosis and endovascular management

M Abdalkader, F Hui, MR Amans, E Raz… - Journal of …, 2023 - Elsevier
The role of the venous circulation in neurological diseases has been underestimated. In this
review, we present an overview of the intracranial venous anatomy, venous disorders of the …

Chronic cerebrospinal venous insufficiency and multiple sclerosis: a comprehensive meta-analysis of case–control studies

G Tsivgoulis, TN Sergentanis, A Chan… - Therapeutic …, 2014 - journals.sagepub.com
Objectives: Chronic cerebrospinal venous insufficiency (CCSVI) has recently been
implicated in the pathogenesis of multiple sclerosis (MS). This comprehensive meta-analysis …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives

R Zivadinov, M Ramanathan, K Dolic… - Expert review of …, 2011 - Taylor & Francis
Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in multiple
sclerosis patients. CCSVI is characterized by impaired brain venous drainage due to outflow …

Cerebral venous disorders: the path forward

KM Fargen, F Hui, JA Hirsch - Journal of neurointerventional surgery, 2023 - jnis.bmj.com
Arterial diseases are well understood to be major causes of morbidity and mortality. High
pressured arteries carry blood, oxygen, and other 'fuels' for organ function. In contrast, the …