Targets for diagnosis, prognosis and therapy of acute myeloid leukemia and myelodysplastic syndromes

UG Steidl, LB De Pujato, W Britta - 2013 - Google Patents
XKTZWUACRZHVAN-VADRZIEHSA-N Interleukin-8 Chemical compound C ([C@ H](NC (=
O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC= 1C2= CC= CC= C2NC= 1) NC (= O)[C …

Methods and Compositons for the Treatment and Diagnosis of Cancer

K Chapman, J Wagner, M West, MD Lacher… - US Patent App. 14 …, 2014 - Google Patents
XKTZWUACRZHVAN-VADRZIEHSA-N Interleukin-8 Chemical compound C ([C@ H](NC (=
O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC= 1C2= CC= CC= C2NC= 1) NC (= O)[C …

Methods and compositions for prognosis and treatment of cancers

L Molinero, P Hegde - US Patent 11,236,394, 2022 - Google Patents
XKTZWUACRZHVAN-VADRZIEHSA-N Interleukin-8 Chemical compound C ([C@ H](NC (=
O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC= 1C2= CC= CC= C2NC= 1) NC (= O)[C …

COMPOSITION FOR THE DIAGNOSIS, PREVENTION OR TREATMENT OF DISEASES RELATED TO CELLS EXPRESSING IL-8 OR GRO-ALPHA, COMPRISING …

JW Chang, YS Yang, WII Oh - US Patent App. 13/680,995, 2013 - Google Patents
XKTZWUACRZHVAN-VADRZIEHSA-N Interleukin-8 Chemical compound C ([C@ H](NC (=
O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC= 1C2= CC= CC= C2NC= 1) NC (= O)[C …

Ligand

G Winter, I Tomlinson, O Ignatovich… - US Patent App. 11 …, 2006 - Google Patents
XKTZWUACRZHVAN-VADRZIEHSA-N Interleukin-8 Chemical compound C ([C@ H](NC (=
O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC= 1C2= CC= CC= C2NC= 1) NC (= O)[C …

High expression of interleukin-2 receptor α-chain (CD25) in myelodysplastic syndrome preceding acute myeloid leukemia and chronic myeloid leukemia in myeloid …

K Nakase, K Kita, T Kyo, N Katayama - Leukemia & Lymphoma, 2017 - Taylor & Francis
A variety of cytokines, including colony-stimulating factors (CSFs) and interleukins (ILs),
have been demonstrated to regulate the survival, growth, differentiation, and apoptosis of …

Prognostic relevance of cytokine receptor expression in acute myeloid leukemia: interleukin-2 receptor α-chain (CD25) expression predicts a poor prognosis

K Nakase, K Kita, T Kyo, T Ueda, I Tanaka… - PLoS …, 2015 - journals.plos.org
A variety of cytokine/cytokine receptor systems affect the biological behavior of acute
leukemia cells. However, little is known about the clinical relevance of cytokine receptor …

Methods and reagents for isolating biologically active peptides

J Gyuris, AJ Morris - US Patent 6,420,110, 2002 - Google Patents
XKTZWUACRZHVAN-VADRZIEHSA-N Interleukin-8 Chemical compound C ([C@ H](NC (=
O)[C@ H](CC (O)= O) NC (= O)[C@ H](CC= 1C2= CC= CC= C2NC= 1) NC (= O)[C …

Novel inhibitor of hematopoietic cell kinase as a potential therapeutic agent for acute myeloid leukemia

FM Roversi, MLP Bueno, JAF da Silva… - Cancer Immunology …, 2022 - Springer
Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are characterized by
risk of relapses, poor survival, unwanted side effects and high toxicity with the current …

The CXCR4 Score: A New Prognostic Marker in Acute Myelogenous Leukemia.

AC Spoo, WG Wierda, JA Burger - Blood, 2004 - Elsevier
Despite major improvements in the understanding and treatment of certain leukemias during
the past years, the overall survival of patients with acute myelogenous leukemia (AML) …