Rational use of antibiotic is the key approach to improve the antibiotic performance and
tackling of the antimicrobial resistance. The efficacy of antimicrobials are influenced by many …

Currently, the efficacy of antibiotics is severely affected by the emergence of the
antimicrobial resistance phenomenon, leading to increased morbidity and mortality …

Introduction: Antimicrobial resistance is a well-recognized global threat; thus, the
development of strong infection control policies coupled with antimicrobial stewardship …

Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

In recent years, due to the dramatic increase in and global spread of bacterial resistance to a
number of commonly used antibacterial agents, many studies have been directed at …

Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …

Highlights•The infection environment influences antibiotic susceptibility.•Clinical
susceptibility assays frequently fail to predict drug efficacy in patients.•Host interactions and …

Antimicrobial resistance, the ability of (pathogenic) bacteria to withstand the action of
antibiotic drugs, has recently been rated of having an impact on humans similar to that of …

Background Antibiotic resistance is currently the most serious global threat to the effective
treatment of bacterial infections. Antibiotic resistance has been established to adversely …

Antimicrobial agents are among the most commonly used and misused of all drugs. The
inevitable consequence of the widespread use of antimicrobial agents has been the …