Uremic toxins: an alarming danger concerning the cardiovascular system
CA Falconi, CVC Junho, F Fogaça-Ruiz… - Frontiers in …, 2021 - frontiersin.org
The kidneys and heart share functions with the common goal of maintaining homeostasis.
When kidney injury occurs, many compounds, the so-called “uremic retention solutes” or …
When kidney injury occurs, many compounds, the so-called “uremic retention solutes” or …
Protein-bound uremic toxins: new insight from clinical studies
S Liabeuf, TB Drüeke, ZA Massy - Toxins, 2011 - mdpi.com
The uremic syndrome is attributed to the progressive retention of a large number of
compounds which, under normal conditions, are excreted by healthy kidneys. The …
compounds which, under normal conditions, are excreted by healthy kidneys. The …
Uremic toxicity: present state of the art
R Vanholder, A Argiles, U Baurmeister… - … journal of artificial …, 2001 - journals.sagepub.com
The uremic syndrome is a complex mixture of organ dysfunctions, which is attributed to the
retention of a myriad of compounds that under normal condition are excreted by the healthy …
retention of a myriad of compounds that under normal condition are excreted by the healthy …
Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets
YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart - Toxins, 2021 - mdpi.com
Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …
[HTML][HTML] New insights in uremic toxins
R Vanholder, G Glorieux, R De Smet, N Lameire - Kidney International, 2003 - Elsevier
New insights in uremic toxins. The retention in the body of compounds, which normally are
secreted into the urine results in a clinical picture, called the uremic syndrome. The retention …
secreted into the urine results in a clinical picture, called the uremic syndrome. The retention …
Cardiotoxicity of uremic toxins: a driver of cardiorenal syndrome
S Lekawanvijit - Toxins, 2018 - mdpi.com
Cardiovascular disease (CVD) is highly prevalent in the setting of chronic kidney disease
(CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac …
(CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac …
An update on uremic toxins
N Neirynck, R Vanholder, E Schepers, S Eloot… - … urology and nephrology, 2013 - Springer
In the last decade, uremic toxicity as a potential cause for the excess of cardiovascular
disease and mortality observed in chronic kidney disease gained more and more interest …
disease and mortality observed in chronic kidney disease gained more and more interest …
Cardiorenal syndrome: the emerging role of protein-bound uremic toxins
Cardiorenal syndrome is a condition in which a complex interrelationship between cardiac
dysfunction and renal dysfunction exists. Despite advances in treatment of both …
dysfunction and renal dysfunction exists. Despite advances in treatment of both …
A bench to bedside view of uremic toxins
R Vanholder, U Baurmeister, P Brunet… - Journal of the …, 2008 - journals.lww.com
Reviewing the current picture of uremic toxicity reveals its complexity. Focusing on
cardiovascular damage as a model of uremic effects resulting in substantial morbidity and …
cardiovascular damage as a model of uremic effects resulting in substantial morbidity and …
Protein-bound uremic toxins: new culprits of cardiovascular events in chronic kidney disease patients
Chronic kidney disease (CKD) has been considered a major risk factor for cardiovascular
diseases. Although great advances have recently been made in the pathophysiology and …
diseases. Although great advances have recently been made in the pathophysiology and …