Transcription initiation is a major regulatory step in eukaryotic gene expression. Co-
activators establish transcriptionally competent promoter architectures and chromatin …

The SAGA (Spt–Ada–Gcn5 acetyltransferase) coactivator complex contains distinct
chromatin-modifying activities and is recruited by DNA-bound activators to regulate the …

Wild-type transcriptional activation by Gcn4p is dependent on multiple coactivators,
including SAGA, SWI/SNF, Srb mediator, CCR4-NOT, and RSC, which are all recruited by …

Abstract SAGA (Spt-Ada-Gcn5 acetyltransferase) is a highly conserved transcriptional
coactivator that consists of four functionally independent modules. Its two distinct enzymatic …

Throughout the last decade, great advances have been made in our understanding of how
DNA-templated cellular processes occur in the native chromatin environment. Proteins that …

Transcriptional activation by Gcn4p is dependent on the coactivators SWI/SNF, SAGA, and
Srb Mediator, which are recruited by Gcn4p and stimulate assembly of the preinitiation …

Transcriptional activators interact with multisubunit coactivators that modify chromatin
structure or recruit the general transcriptional machinery to their target genes. Budding yeast …

The yeast SAGA (Spt–Ada–Gcn5–acetyltransferase) coactivator complex exerts functions in
gene expression, including activator interaction, histone acetylation, histone …

There are many large protein complexes involved in transcription in a chromatin context.
However, recent studies on the SAGA coactivator complex are generating new paradigms …

The Spt–Ada–Gcn5–acetyltransferase (SAGA) complex was discovered from
Saccharomyces c erevisiae and has been well characterized as an important transcriptional …