X-ray diffraction study of lipid bilayer membranes interacting with amphiphilic helical peptides: diphytanoyl phosphatidylcholine with alamethicin at low concentrations
A variety of amphiphilic helical peptides have been shown to exhibit a transition from
adsorbing parallel to a membrane surface at low concentrations to inserting perpendicularly …
adsorbing parallel to a membrane surface at low concentrations to inserting perpendicularly …
[HTML][HTML] Lipid shape is a key factor for membrane interactions of amphipathic helical peptides
E Strandberg, D Tiltak, S Ehni, P Wadhwani… - … et Biophysica Acta (BBA …, 2012 - Elsevier
The membrane alignment of the amphiphilic α-helical model peptide MSI-103 (sequence
[KIAGKIA] 3-NH2) was examined by solid state 2H-NMR in different lipid systems by …
[KIAGKIA] 3-NH2) was examined by solid state 2H-NMR in different lipid systems by …
Orientation of α-helical peptides in a lipid bilayer
JC Huschilt, BM Millman, JH Davis - Biochimica et Biophysica Acta (BBA) …, 1989 - Elsevier
Samples of pure lipid (dipalmitoylphosphatidylcholine) and lipid containing short α-helical
peptides were oriented and examined by X-ray diffraction, together with unoriented samples …
peptides were oriented and examined by X-ray diffraction, together with unoriented samples …
Effect of changing the size of lipid headgroup on peptide insertion into membranes
Adsorption of amphiphilic peptides to the headgroup region of a lipid bilayer is a common
mode of protein-membrane interactions. Previous studies have shown that adsorption …
mode of protein-membrane interactions. Previous studies have shown that adsorption …
Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides
RM Epand, Y Shai, JP Segrest… - … Original Research on …, 1995 - Wiley Online Library
The amphipathic helix, in which hydrophobia and hydrophilic residues are grouped on
opposing faces, is a structural mot if found in many peptides and proteins that bind to …
opposing faces, is a structural mot if found in many peptides and proteins that bind to …
Elasticity of lipid bilayer interacting with amphiphilic helical peptides
HW Huang - Journal de Physique II, 1995 - jp2.journaldephysique.org
Amphiphilic helical peptides exhibit an insertion transition when they interact with lipid
bilayers. At low concentrations, the peptides adsorb at the hydrophilic-hydrophobic interface …
bilayers. At low concentrations, the peptides adsorb at the hydrophilic-hydrophobic interface …
Mechanism of alamethicin insertion into lipid bilayers
Alamethicin adsorbs on the membrane surface at low peptide concentrations. However,
above a critical peptide-to-lipid ratio (P/L), a fraction of the peptide molecules insert in the …
above a critical peptide-to-lipid ratio (P/L), a fraction of the peptide molecules insert in the …
[HTML][HTML] General aspects of peptide selectivity towards lipid bilayers and cell membranes studied by variation of the structural parameters of amphipathic helical model …
M Dathe, J Meyer, M Beyermann, B Maul… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Model compounds of modified hydrophobicity (H), hydrophobic moment (μ) and angle
subtended by charged residues (Φ) were synthesized to define the general roles of …
subtended by charged residues (Φ) were synthesized to define the general roles of …
Interaction of a synthetic amphiphilic polypeptide and lipids in a bilayer structure
JH Davis, DM Clare, RS Hodges, M Bloom - Biochemistry, 1983 - ACS Publications
James H. Davis,* Donna M. Clare, Robert S. Hodges, and Myer Bloom abstract: A unique
model-membrane system composed of synthetic amphiphilic peptides, as models of …
model-membrane system composed of synthetic amphiphilic peptides, as models of …
Induction of nonbilayer structures in diacylphosphatidylcholine model membranes by transmembrane α-helical peptides: importance of hydrophobic mismatch and …
JA Killian, I Salemink, MRR de Planque… - Biochemistry, 1996 - ACS Publications
We have investigated the effect of several hydrophobic polypeptides on the phase behavior
of diacylphosphatidylcholines with different acyl chain length. The polypeptides are …
of diacylphosphatidylcholines with different acyl chain length. The polypeptides are …