The oral delivery of drugs is the most popular route of administration for patients. However,
thymopentin (TP5) is only available in the market in forms for parenteral administration as an …

Background: Although its immunomodulatory properties make thymopentin (TP5) appealing,
its rapid metabolism and inactivation in the digestive system pose significant challenges for …

The oral delivery of medicines is the most popular route of administration for patients.
However, thymopentin (TP5) is only available in the market in forms for parenteral …

Formulation of protein and peptide drugs with sustained release properties is crucial to
enhance their therapeutic effect and minimize administration frequency. In this study …

The purpose of this study was to design and evaluate lectin-conjugated PLGA nanoparticles
for oral delivery of thymopentin. Thymopentin loaded PLGA nanoparticles (TP5–NPs) were …

Abstract Thymopentin (TP5), a clinically used immunomodulatory pentapeptide, can
efficiently promote thymocyte differentiation and influence mature T-cell function, thus …

This study was done to prepare thymopentin (TP5)-loaded poly (butyl cyanoacrylate)
nanoparticles (TP5-PBCA-NPs) and evaluate thier efficacy for oral delivery. TP5-PBCA-NPs …

Peptides, although high efficacy and specificity in their physiological function, usually have
low therapeutical activities due to their poor bioavailability when administrated orally …

Thymopentin, a potent immunomodulating drug, was incorporated into pH-sensitive chitosan
nanoparticles prepared by ionic gelation of chitosan with tripolyphosphate anions and then …

Thymopentin (TP5) is a synthetic pentapeptide with immunomodulatory properties. Given
the previously described poor absorption of TP5, preformulation data is required to support …