Abnormal synergies and associated reactions post-hemiparetic stroke reflect muscle activation patterns of brainstem motor pathways

LM McPherson, JPA Dewald - Frontiers in neurology, 2022 - frontiersin.org
Individuals with moderate-to-severe post-stroke hemiparesis cannot control proximal and
distal joints of the arm independently because they are constrained to stereotypical …

[HTML][HTML] A neuroanatomical framework for upper limb synergies after stroke

AJC McMorland, KD Runnalls… - Frontiers in human …, 2015 - frontiersin.org
Muscle synergies describe common patterns of co-or reciprocal activation that occur during
movement. After stroke, these synergies change, often in stereotypical ways. The …

Neuromodulatory inputs to motoneurons contribute to the loss of independent joint control in chronic moderate to severe hemiparetic stroke

JG McPherson, MD Ellis, RN Harden… - Frontiers in …, 2018 - frontiersin.org
In chronic hemiparetic stroke, increased shoulder abductor activity causes involuntary
increases in elbow, wrist, and finger flexor activation, an abnormal muscle coactivation …

Progressive recruitment of contralesional cortico‐reticulospinal pathways drives motor impairment post stroke

JG McPherson, A Chen, MD Ellis, J Yao… - The Journal of …, 2018 - Wiley Online Library
Key points Activation of the shoulder abductor muscles in the arm opposite a unilateral brain
injury causes involuntary increases in elbow, wrist and finger flexion in the same arm, a …

[HTML][HTML] Cortex integrity relevance in muscle synergies in severe chronic stroke

E García-Cossio, D Broetz, N Birbaumer… - Frontiers in human …, 2014 - frontiersin.org
Background: Recent experimental evidence has indicated that the motor system coordinates
muscle activations through a linear combination of muscle synergies that are specified at the …

Stability of muscle synergies for voluntary actions after cortical stroke in humans

VCK Cheung, L Piron, M Agostini… - Proceedings of the …, 2009 - National Acad Sciences
Production of voluntary movements relies critically on the functional integration of several
motor cortical areas, such as the primary motor cortex, and the spinal circuitries …

Impaired muscle phasing systematically adapts to varied relative angular relationships during locomotion in people poststroke

L Alibiglou, DA Brown - Journal of neurophysiology, 2011 - journals.physiology.org
After stroke, hemiparesis will result in impairments to locomotor control. Specifically, muscle
coordination deficits, in the form of inappropriately phased muscle-activity patterns, occur in …

The increase in overlap of cortical activity preceding static elbow/shoulder motor tasks is associated with limb synergies in severe stroke

J Yao, JPA Dewald - Neurorehabilitation and neural repair, 2018 - journals.sagepub.com
The loss of independent joint control, clinically referred to as limb synergies, is prevalent in
the paretic upper limb of individuals with chronic hemiparetic stroke. To understand the …

Contributions of altered stretch reflex coordination to arm impairments following stroke

RD Trumbower, VJ Ravichandran… - Journal of …, 2010 - journals.physiology.org
Patterns of stereotyped muscle coactivation, clinically referred to as synergies, emerge
following stroke and impair arm function. Although researchers have focused on cortical …

Understanding motor impairment in the paretic lower limb after a stroke: a review of the literature

N Arene, J Hidler - Topics in stroke rehabilitation, 2009 - Taylor & Francis
In addition to muscle weakness caused by injury to supraspinal centers, several
mechanisms may contribute to motor impairment in the paretic lower limb following a stroke …