[HTML][HTML] Targeting inhibition of prognosis-related lipid metabolism genes including CYP19A1 enhances immunotherapeutic response in colon cancer
L Liu, M Mo, X Chen, D Chao, Y Zhang, X Chen… - Journal of Experimental …, 2023 - Springer
Background Lipid metabolic reprogramming in colon cancer shows a potential impact on
tumor immune microenvironment and is associated with response to immunotherapy …
tumor immune microenvironment and is associated with response to immunotherapy …
[HTML][HTML] Molecular subtype identification and prognosis stratification by a metabolism-related gene expression signature in colorectal cancer
Background Metabolic reprograming have been associated with cancer occurrence and
progression within the tumor immune microenvironment. However, the prognostic potential …
progression within the tumor immune microenvironment. However, the prognostic potential …
[HTML][HTML] Single-cell transcriptome analysis reveals heterogeneity and convergence of the tumor microenvironment in colorectal cancer
S Xie, Y Cai, D Chen, Y Xiang, W Cai, J Mao… - Frontiers in …, 2023 - frontiersin.org
Introduction Colorectal cancer (CRC) ranks second for mortality and third for morbidity
among the most commonly diagnosed cancers worldwide. We aimed to investigate the …
among the most commonly diagnosed cancers worldwide. We aimed to investigate the …
[PDF][PDF] An immunometabolism subtyping system identifies S100A9+ macrophage as an immune therapeutic target in colorectal cancer based on multiomics analysis
X Bao, D Wang, X Dai, C Liu, H Zhang, Y Jin… - Cell Reports …, 2023 - cell.com
Immunometabolism in the tumor microenvironment (TME) and its influence on the
immunotherapy response remain uncertain in colorectal cancer (CRC). We perform …
immunotherapy response remain uncertain in colorectal cancer (CRC). We perform …
[HTML][HTML] Characterization of the fatty acid metabolism in colorectal cancer to guide clinical therapy
C Ding, Z Shan, M Li, H Chen, X Li, Z Jin - Molecular Therapy-Oncolytics, 2021 - cell.com
Colorectal cancer (CRC) is one of the most common malignant tumors, with the second-
highest mortality of all 36 cancers worldwide. The roles of fatty acid metabolism in CRC were …
highest mortality of all 36 cancers worldwide. The roles of fatty acid metabolism in CRC were …
[HTML][HTML] Role of a lipid metabolism-related lncRNA signature in risk stratification and immune microenvironment for colon cancer
Y Lin, Y Xiao, S Liu, L Hong, L Shao, J Wu - BMC Medical Genomics, 2022 - Springer
Background Energy metabolism disorder, especially lipid metabolism disorder, is an
important biological characteristic of colon cancer. This research sought to examine the …
important biological characteristic of colon cancer. This research sought to examine the …
[HTML][HTML] Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data
Y Hao, D Li, Y Xu, J Ouyang, Y Wang, Y Zhang, B Li… - BMC …, 2019 - Springer
Background Lipid metabolism reprogramming is a hallmark for tumor which contributes to
tumorigenesis and progression, but the commonality and difference of lipid metabolism …
tumorigenesis and progression, but the commonality and difference of lipid metabolism …
[HTML][HTML] A six lipid metabolism related gene signature for predicting the prognosis of hepatocellular carcinoma
K Xu, P Xia, P Liu, X Zhang - Scientific Reports, 2022 - nature.com
Globally, hepatocellular carcinoma (HCC) is one of the most lethal malignant tumors.
Studies have shown that alterations in the tumor immune microenvironment (TIME) play a …
Studies have shown that alterations in the tumor immune microenvironment (TIME) play a …
[HTML][HTML] Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
O Østrup, VJ Dagenborg, EA Rødland, V Skarpeteig… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Metastatic colorectal cancer (CRC) is associated with highly variable clinical
outcome and response to therapy. The recently identified consensus molecular subtypes …
outcome and response to therapy. The recently identified consensus molecular subtypes …
In silico development and clinical validation of novel 8 gene signature based on lipid metabolism related genes in colon adenocarcinoma
C Jiang, Y Liu, S Wen, C Xu, L Gu - Pharmacological research, 2021 - Elsevier
Background Changes in lipid metabolism pathways play a major role in colon
carcinogenesis and development. Hence, we conducted a systematic analysis of lipid …
carcinogenesis and development. Hence, we conducted a systematic analysis of lipid …
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