Turbulence and blood washout in presence of mitral regurgitation: a computational fluid-dynamics study in the complete left heart

L Bennati, V Giambruno, F Renzi, V Di Nicola… - bioRxiv, 2023 - biorxiv.org
In this work we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation …

Turbulent blood dynamics in the left heart in the presence of mitral regurgitation: a computational study based on multi-series cine-MRI

L Bennati, V Giambruno, F Renzi, V Di Nicola… - … and Modeling in …, 2023 - Springer
In this work, we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation. We …

An Image Based Computational Fluid Dynamics Study of Mitral Valve. A novel Approach to Assess the Mitral Valve, from Physiology to Surgical Practice

V Giambruno - 2023 - iris.univr.it
Mitral valve disease is the second most frequent valve disease requiring surgery. The aim of
our study was to develop through a computational fluid dynamics a method to study the …

An image-based computational fluid dynamics study of mitral regurgitation in presence of prolapse

L Bennati, C Vergara, V Giambruno, I Fumagalli… - Cardiovascular …, 2023 - Springer
Purpose In this work we performed an imaged-based computational study of the systolic
fluid dynamics in presence of mitral valve regurgitation (MVR). In particular, we compared …

Computational analysis of flow structures in turbulent ventricular blood flow associated with mitral valve intervention

J Kronborg, F Svelander, S Eriksson-Lidbrink… - Frontiers in …, 2022 - frontiersin.org
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis
events due to a modified blood flow in the heart, and thereby a change in the mechanical …

Mathematical and numerical models for the fluid dynamics of the human heart

A Zingaro - 2021 - politesi.polimi.it
Computer-based numerical simulations-also known as in silico simulations-of the heart and
blood circulation represent a valuable tool to analyze the cardiac function and to enhance …

Hemodynamic Assessment of the Pathological Left Ventricle Function under Rest and Exercise Conditions

J Korte, T Rauwolf, JN Thiel, A Mitrasch, P Groschopp… - Fluids, 2023 - mdpi.com
Purpose: The analysis of pathological human left ventricular hemodynamics using high-
resolved image-based blood flow simulations shows a major potential for examining mitral …

Image-based simulations show important flow fluctuations in a normal left ventricle: what could be the implications?

C Chnafa, S Mendez, F Nicoud - Annals of biomedical engineering, 2016 - Springer
Intra-cardiac flow has been explored for decades but there is still no consensus on whether
or not healthy left ventricles (LV) may harbour turbulent-like flow despite its potential …

Using image-based CFD to investigate the intracardiac turbulence

C Chnafa, S Mendez, R Moreno, F Nicoud - Modeling the Heart and the …, 2015 - Springer
A numerical framework designed to compute the blood flow in patient-specific human hearts
is presented. The geometry of the heart cavities and associated wall motion are extracted …

Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle

C Papolla, A Darwish, L Kadem, R Rieu - Cardiovascular Engineering and …, 2020 - Springer
Purpose Mitral regurgitation (MR) is the second most common valve disease in
industrialized countries. Despite its high prevalence, little is known about its impact on the …