Microtubules are key cytoskeletal elements of all eukaryotic cells and are assembled of
evolutionarily conserved α-tubulin–β-tubulin heterodimers. Despite their uniform structure …

Microtubules are cytoskeletal filaments that are dynamically assembled from α/β-tubulin
heterodimers. The primary sequence and structure of the tubulin proteins and, consequently …

Microtubules are core components of the eukaryotic cytoskeleton with essential roles in cell
division, shaping, motility and intracellular transport. Despite their functional heterogeneity …

Microtubules exhibit dynamic instability, converting abruptly between assembly and
disassembly with continued growth dependent on the presence of a tubulin–GTP cap at the …

Although most eukaryotic cells can express multiple isotypes of αβ-tubulin, the significance
of this diversity has not always been apparent. Recent data indicate that particular αβ-tubulin …

The microtubule cytoskeleton is assembled from the α-and β-tubulin subunits of the
canonical tubulin heterodimer, which polymerizes into microtubules, and a small number of …

Across different cell types and tissues, microtubules are assembled from highly conserved
dimers of α‐and β‐tubulin. Despite their highly similar structures, microtubules have …

Microtubules perform essential and diverse functions in eukaryotic cells. They are required
for spindles during mitosis and meiosis, for axonal transport, for organelle positioning, and …

Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …

The αβ-tubulin heterodimer, the building block of microtubules, is subject to a large number
of post-translational modifications, comparable in diversity to the intensively studied histone …