Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling

YRV Shih, YS Hwang, A Phadke… - Proceedings of the …, 2014 - National Acad Sciences
Synthetic matrices emulating the physicochemical properties of tissue-specific ECMs are
being developed at a rapid pace to regulate stem cell fate. Biomaterials containing calcium …

Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells

P Wang, L Zhao, J Liu, MD Weir, X Zhou, HHK Xu - Bone research, 2014 - nature.com
Tissue engineering is promising to meet the increasing need for bone regeneration.
Nanostructured calcium phosphate (CaP) biomaterials/scaffolds are of special interest as …

Probing the Osteoinductive Effect of Calcium Phosphate by Using an In Vitro Biomimetic Model

YC Chai, SJ Roberts, J Schrooten… - Tissue Engineering Part …, 2011 - liebertpub.com
The use of calcium phosphate (CaP)-based carriers in bone engineering is a promising
approach to induce in vivo bone formation. However, the exact mechanism of osteoinduction …

Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies

YC Chai, A Carlier, J Bolander, SJ Roberts, L Geris… - Acta biomaterialia, 2012 - Elsevier
Calcium phosphate (CaP) has traditionally been used for the repair of bone defects because
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …

[HTML][HTML] Calcium phosphate-based materials regulate osteoclast-mediated osseointegration

X Wang, Y Yu, L Ji, Z Geng, J Wang, C Liu - Bioactive Materials, 2021 - Elsevier
Calcium phosphate-based materials (CaP) have been widely used as bone graft substitutes
with a decent osseointegration. However, the mechanism whereby cells function and repair …

Calcium phosphates and angiogenesis: implications and advances for bone regeneration

A Malhotra, P Habibovic - Trends in biotechnology, 2016 - cell.com
Calcium phosphates (CaPs) are among the most utilized synthetic biomaterials for bone
regeneration, largely owing to their established osteoconductive and osteoinductive …

The osteoinductivity of calcium phosphate-based biomaterials: a tight interaction with bone healing

Y Zhang, T Shu, S Wang, Z Liu, Y Cheng… - … in Bioengineering and …, 2022 - frontiersin.org
Calcium phosphate (CaP)-based bioceramics are the most widely used synthetic
biomaterials for reconstructing damaged bone. Accompanied by bone healing process …

Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

S Bose, G Fielding, S Tarafder… - Trends in …, 2013 - cell.com
General trends in synthetic bone grafting materials are shifting towards approaches that can
illicit osteoinductive properties. Pharmacologics and biologics have been used in …

Injectable calcium phosphate scaffold with iron oxide nanoparticles to enhance osteogenesis via dental pulp stem cells

Y Xia, H Chen, F Zhang, L Wang, B Chen… - Artificial cells …, 2018 - Taylor & Francis
Literature search revealed no systematic report on iron oxide nanoparticle-incorporating
calcium phosphate cement scaffolds (IONP-CPC). The objectives of this study were to:(1) …

Calcium phosphate-based biomaterials for bone repair

X Hou, L Zhang, Z Zhou, X Luo, T Wang… - Journal of functional …, 2022 - mdpi.com
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …