Spinal cord injury (SCI) is a devastating condition that results in sensory and motor
dysfunctions below the injury site. Currently, there is no effective treatment. Extracellular …

Background Uncontrollable inflammation and nerve cell apoptosis are the most destructive
pathological response after spinal cord injury (SCI). So, inflammation suppression combined …

Persistence of inflammation during the secondary injury of spinal cord injury (SCI) has been
identified as the root cause of poor regenerative capability of spinal cord. M2 microglia …

Background: The formation of an inhibitory inflammatory microenvironment after spinal cord
injury (SCI) remains a great challenge for nerve regeneration. The poor local …

Spinal cord injuries (SCI) often cause severe inflammatory response and neuronal loss,
which consequently deteriorates motor function. Although exogenous stem cells are …

Inhibition of oxidative stress and inflammatory responses caused by secondary injury
following traumatic spinal cord injury (SCI) is an attractive strategy in treating traumatic SCI …

Secondary injury has a tremendous impact on the recovery of motor function after traumatic
spinal cord injury (SCI). The microenvironmental reactive oxygen species (ROS) and …

Spinal cord injury (SCI) is a devastating trauma that leads to irreversible motor and sensory
dysfunction and is, so far, without effective treatment. Recently, however, nano‐sized …

Current approaches for treating spinal cord injury (SCI) are mainly based on cell
transplantation. Mesenchymal stem cells (MSCs) can help slow the progression of SCI due …

Secondary neuroinflammation caused by proinflammatory microglia exacerbates the
disability of patients with spinal cord injury (SCI), while low drug delivery efficiency reduces …