In recent years we have witnessed a major interest in the study of the role of mitochondria,
not only as ATP producers through oxidative phosphorylation but also as regulators of …

Mitochondria are the powerhouse of the cell. Their primary physiological function is to
generate adenosine triphosphate through oxidative phosphorylation via the electron …

The biochemical pathways to cell death in chronic and acute forms of neurodegeneration
are poorly understood, limiting the ability to develop effective therapeutic approaches. As …

Mitochondria play a central role in cell biology not only as producers of ATP, but also in the
sequestration of Ca2+ and the generation of free radicals. They are also repositories of …

Mitochondria are the powerhouse of the cell. Their primary physiological function is to
generate ATP through oxidative phosphorylation via the electron transport chain. Reactive …

Mitochondria are active in the continuous generation of reactive oxygen species (ROS),(eg,
superoxide), thereby favouring a situation of mitochondrial oxidative stress. Under oxidative …

Mitochondrial dysfunctions are supposed to be responsible for many neurodegenerative
diseases dominating in Alzheimer's disease (AD), Parkinson's disease (PD), and …

Mitochondria are key cell organelles in that they are responsible for energy production and
control many processes from signalling to cell death. The function of the mitochondrial …

Mitochondria are best known for their role in ATP generation. However, studies over the past
two decades have shown that mitochondria do much more than that. Mitochondria regulate …

Although oxidative stress and mitochondrial dysfunction have been linked to
neurodegenerative diseases such as Alzheimer's disease (AD), it remains unclear how …