Human atrial fibrillation (AF) is the most common sustained clinically observed cardiac
arrhythmia causing mortality and morbidity in patients with increasing incidence in the …

Atrial fibrillation (AF) is the most common sustained heart rhythm disturbance, associated
with substantial morbidity and mortality (Andrade et al., 2014). The current prevalence of AF …

Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today.
This book presents multi-scale computational methods to advance our understanding of …

Ionic mechanisms underlying atrial fibrillation (AF) generation and propagation are unclear.
In this study, we investigate the dependence of AF related properties to changes in human …

Investigation of the development of atrial fibrillation in-vivo is difficult as the occurrence is
spontaneous and ECG signals of the atria are complex during fibrillation. In this study the …

Chronic atrial fibrillation (AF) is a complex disease with underlying changes in
electrophysiology, calcium signaling and the structure of atrial myocytes. How these …

Atrial fibrillation (AF) is the world's most common cardiac arrhythmia. Due to the complexity
of the heart and highly irregular electrical activity during AF it is a grand challenge to …

Atrial Fibrillation (AF) is the most common cardiac arrhythmia worldwide; it is complex and
can be multifactorial, and the underlying mechanisms are not yet completely understood …

The excitation, contraction, and relaxation of an atrial cardiomyocyte are maintained by the
activation and inactivation of numerous cardiac ion channels. Their collaborative efforts …

Cardiac tissue conduction velocity (CV) is a relevant variable in the maintenance and
stability of atrial fibrillation (AF). The main goal of this work is to investigate modulation of CV …