White matter hyperintensities (WMHs) are a risk factor for cognitive decline. Physical activity
(PA) is associated with lower WMH. Whether long-term exposure to PA programs has …

Importance In the absence of disease-modifying therapies for Alzheimer disease, there is a
critical need to identify modifiable risk factors that may delay the progression of Alzheimer …

Context Many observational studies have shown that physical activity reduces the risk of
cognitive decline; however, evidence from randomized trials is lacking. Objective To …

Introduction Physical activity (PA) is associated with brain health in older adults. However, it
is unknown whether the current physical activity recommendations (PAR) impart substantive …

Background Observational studies have documented a potential protective effect of physical
exercise in older adults who are at risk for developing Alzheimer's disease. The Fitness for …

Introduction The associations between self-reported current and past leisure time physical
activity (LTPA) and Alzheimer's disease (AD) incidence were determined using data from the …

Objective Physical activity (PA) is beneficial in reductions of all-cause mortality and
dementia. However, whether Alzheimer's disease (AD) risk is modified by PA remains …

Objectives Since physical activity (PA) has demonstrated benefits for cardiovascular health,
it is possible to hypothesize that higher or increasing PA slows the progression of white …

Physical activity has been associated with decreased dementia risk in recent studies, but the
effects for structural brain changes (ie white matter lesions (WMLs) and/or brain atrophy) …

Objectives To examine the association between physical activity (PA) and Alzheimer
disease (AD) course. Background PA has been related to lower risk for AD. Whether PA is …