EGFR Status Assessment for Better Care of Early Stage Non-Small Cell Lung Carcinoma: What Is Changing in the Daily Practice of Pathologists?

P Hofman - Cells, 2021 - mdpi.com
The recent emergence of novel neoadjuvant and/or adjuvant therapies for early stage (I-IIIA)
non-small cell lung carcinoma (NSCLC), mainly tyrosine kinase inhibitors (TKIs) targeting …

Targeted therapy and immunotherapy in early-stage non-small cell lung cancer: current evidence and ongoing trials

M de Scordilli, A Michelotti, E Bertoli… - International journal of …, 2022 - mdpi.com
The scenario of neoadjuvant and adjuvant settings in non-small cell lung cancer (NSCLC) is
rapidly evolving. As already happened for the advanced disease, also early stages have …

Targeted Therapies in Early-Stage Resectable Non–Small-Cell Lung Cancer: New Kids on the Block

J Liu, A Amini, A Govindarajan, T Abuali… - JCO Precision …, 2023 - ascopubs.org
PURPOSE With increased adoption of next-generation sequencing, tailored therapy on the
basis of molecular status is being delivered for patients with early-stage resectable non …

EGFR Mutations and PD-L1 Expression in Early-Stage Non-Small Cell Lung Cancer: A Real-World Data From a Single Center in Brazil

I Alves Pinto, R de Oliveira Cavagna… - The …, 2022 - academic.oup.com
Background Targeted and immunotherapies are currently moving toward early-stage
settings for patients with non-small cell lung cancer (NSCLC). Predictive biomarkers data …

[PDF][PDF] Pathological diagnosis and molecular testing in non-small cell lung cancer: Belgian guidelines

P Pauwels, M Remmelink, D Hoton, J Van Dorpe… - Belg J Med Oncol, 2016 - bjmo.be
Introduction Lung cancer remains one of the most commonly diagnosed malignancies
worldwide and the leading cause of cancer-related death. 1 Until the last decade, non-small …

[HTML][HTML] The evolving landscape of biomarker testing for non-small cell lung cancer in Europe

KM Kerr, F Bibeau, E Thunnissen, J Botling, A Ryška… - Lung Cancer, 2021 - Elsevier
The discovery of oncogenic driver mutations rendering non-small cell lung cancer (NSCLC)
targetable by small-molecule inhibitors, and the development of immunotherapies, have …

[HTML][HTML] Defining the role of tyrosine kinase inhibitors in early stage non-small cell lung cancer

S Lampaki, G Lazaridis, K Zarogoulidis… - Journal of …, 2015 - ncbi.nlm.nih.gov
Historical, the non-small cell lung cancer (NSCLC) was as a united disease entity and the
chemotherapy to the metastatic cancer had limited results. Recent studies for the metastatic …

[HTML][HTML] Changes in store for early-stage non-small cell lung cancer

JE Sandler, A D'Aiello, B Halmos - Journal of Thoracic Disease, 2019 - ncbi.nlm.nih.gov
The management of advanced non-small cell lung cancer (NSCLC) has been revolutionized
in recent years with the introduction of biomarker-targeted molecular therapies and immune …

[HTML][HTML] Molecular testing in stage I–III non-small cell lung cancer: Approaches and challenges

C Aggarwal, L Bubendorf, WA Cooper, P Illei… - Lung Cancer, 2021 - Elsevier
Precision medicine in non-small cell lung cancer (NSCLC) is a rapidly evolving area, with
the development of targeted therapies for advanced disease and concomitant molecular …

Eventual role of EGFR-tyrosine kinase inhibitors in early-stage non-small-cell lung cancer

D Marquez-Medina, S Popat - Future Oncology, 2016 - Taylor & Francis
Nonadvanced non-small-cell lung cancer (NSCLC) has a poor long-term survival from
surgery or definitive radiation that is minimally improved with induction/adjuvant …