Transcriptomics uncovers key genes for photodynamic killing on Trichosporon asahii biofilms

W Luo, G Wang, H Chang, G Liu, H Zhu, H Li - 2023 - researchsquare.com
The escalating threat of antifungal resistance stemming from Trichosporon asahii (T. asahii)
biofilms necessitates the pursuit of innovative therapeutic strategies. Among these …

Comparative Transcriptome Analysis of T. rubrum, T. mentagrophytes, and M. gypseum Dermatophyte Biofilms in Response to Photodynamic Therapy

B Chen, J Zhang, J Li, Y Qian, B Huang, X Wu - Mycopathologia, 2024 - Springer
Dermatophyte biofilms frequently count for inadequate responses and resistance to
standard antifungal treatments, resulting in refractory chronic onychomycosis infection …

Combinatory Effect of ALA‐PDT and Itraconazole Treatment for Trichosporon asahii

Y Lan, S Lu, B Zheng, Z Tang, J Li… - Lasers in Surgery and …, 2021 - Wiley Online Library
Background and Objectives Trichosporiosis is an opportunistic infection that includes
superficial infections, white piedra, hypersensitivity pneumonitis, and invasive …

Nanoparticle-Based Photodynamic Inhibition of Candida albicans Biofilms with Interfering Quorum Sensing

N Tang, S Yuan, Y Luo, AJ Wang, K Sun, NN Liu… - ACS …, 2023 - ACS Publications
Biofilm formation is a critical event in the pathogenesis and virulence of fungal infections
caused by Candida albicans, giving rise to about a 1000-fold increase in the resistance to …

The inhibitory activity of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) on Candida albicans biofilms

H Shi, J Li, C Peng, B Xu, H Sun - Photodiagnosis and Photodynamic …, 2021 - Elsevier
Abstract Background Biofilm-associated Candida albicans (C. albicans) infections are hard
to cure due to their high levels of resistance to antifungal agents. Photodynamic therapy …

Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform

T Dai, BB Fuchs, JJ Coleman, RA Prates… - Frontiers in …, 2012 - frontiersin.org
Opportunistic fungal pathogens may cause superficial or serious invasive infections,
especially in immunocompromised and debilitated patients. Invasive mycoses represent an …

Effect of 5-Aminolevulinic Acid Photodynamic Therapy on Aspergillus fumigatus Biofilms in Vitro

Z Duan, J Tong, N Zheng, R Zeng, Y Liu, M Li - Current Microbiology, 2023 - Springer
Aspergillus fumigatus biofilm development results in enhanced pathogenicity and treatment
resistance. Most contemporary antibiotics, however, are unable to eliminate biofilms. In …

[PDF][PDF] Visible lights combined with photosensitizing compounds are effective against Candida albicans biofilms. Microorganisms. 2021; 9: 500

P Bapat, G Singh, CJ Nobile - 2021 - academia.edu
Fungal infections are increasing in prevalence worldwide, especially in
immunocompromised individuals. Given the emergence of drug-resistant fungi and the fact …

Photodynamic inactivation against the critical priority pathogen Candida auris

AR Silva, FV Cabral, CR Silva, DFT Silva, AZ Freitas… - repositorio.ipen.br
Fungal pathogens and their associated infections present a growing challenge to global
public health. Among these pathogens, Candida auris has emerged as a highly hazardous …

An in vitro model to study the effect of 5-aminolevulinic acid-mediated photodynamic therapy on Staphylococcus aureus biofilm

KQ Zhao, Y Wu, YX Yi, SJ Feng, RY Wei, Y Ma… - JoVE (Journal of …, 2018 - jove.com
Staphylococcus aureus (S. aureus) is a common human pathogen, which causes pyogenic
and systemic infections. S. aureus infections are difficult to eradicate not only due to the …