Highlights•Cytochrome P450 enzymes catalyse oxygen insertion into a wide range of
substrates.•Mutagenesis of P450s frequently allows novel substrate recognition.•P450s …

Oxidations are key reactions in chemical syntheses. Biooxidations using fermentation
processes have already conquered some niches in industrial oxidation processes since they …

Highlights•Recent applications of P450 enzymes in natural product biosynthesis.•New
strategies for reconstitution of P450 activity in heterologous hosts.•Creation of new P450 …

Cytochromes P450 (P450 or CYP) are heme-containing enzymes that catalyze the
introduction of one atom of molecular oxygen into nonactivated C–H bonds, often in a regio …

The remarkable chemical reactivity and substrate range displayed by cytochromes P450
(P450s) renders them attractive as potential catalysts for a host of challenging chemical …

Cytochromes P450, a family of heme-containing monooxygenases that catalyze a diverse
range of oxidative reactions, are so-called due to their maximum absorbance at 450 nm …

Biocatalytic reactions performed by cytochrome P450 monooxygenases are interesting in
pharmaceutical research since they are involved in human drug metabolism. Furthermore …

Recent studies on microbial cytochrome P450 enzymes have covered several new areas.
Advances have been made in structure–function analysis and new non-enzymatic …

The use of cytochrome P450 (P450 or CYP) enzymes as biocatalysts for the production of
fine chemicals, including pharmaceuticals, has been of increasing interest, primarily owing …

Cytochrome P450 enzymes are renowned for their ability to insert oxygen into an enormous
variety of compounds with a high degree of chemo-and regio-selectivity under mild …