[HTML][HTML] Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies

NC Noronha, A Mizukami, C Caliári-Oliveira… - Stem cell research & …, 2019 - Springer
Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …

[HTML][HTML] Mesenchymal stromal cell therapeutic delivery: translational challenges to clinical application

H Caplan, SD Olson, A Kumar, M George… - Frontiers in …, 2019 - frontiersin.org
For several decades, multipotent mesenchymal stromal cells (MSCs) have been extensively
studied for their therapeutic potential across a wide range of diseases. In the preclinical …

[HTML][HTML] Mesenchymal stromal cell-based therapy: new perspectives and challenges

M Najar, F Bouhtit, R Melki, H Afif, A Hamal… - Journal of clinical …, 2019 - mdpi.com
Stem cells have been the focus of intense research opening up new possibilities for the
treatment of various diseases. Mesenchymal stromal cells (MSCs) are multipotent cells with …

[HTML][HTML] Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress

X Wu, J Jiang, Z Gu, J Zhang, Y Chen, X Liu - Stem cell research & …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

Strategies to address mesenchymal stem/stromal cell heterogeneity in immunomodulatory profiles to improve cell-based therapies

CM Dunn, S Kameishi, DW Grainger, T Okano - Acta Biomaterialia, 2021 - Elsevier
Mesenchymal stromal cells (MSCs) have gained immense attention over the past two
decades due to their multipotent differentiation potential and pro-regenerative and …

Mesenchymal stem cell functionalization for enhanced therapeutic applications

D Kouroupis, C Sanjurjo-Rodriguez… - … Engineering Part B …, 2019 - liebertpub.com
To date, the therapeutic efficacy of human mesenchymal stem cells (hMSCs) has been
investigated in various clinical trials with moderate or, in some cases, inconsistent results …

[HTML][HTML] Different priming strategies improve distinct therapeutic capabilities of mesenchymal stromal/stem cells: Potential implications for their clinical use

V Miceli, G Zito, M Bulati, A Gallo, R Busà… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
Mesenchymal stromal/stem cells (MSCs) have shown significant therapeutic potential, and
have therefore been extensively investigated in preclinical studies of regenerative medicine …

Mesenchymal stromal cells; a new horizon in regenerative medicine

S Tavakoli, HR Ghaderi Jafarbeigloo… - Journal of cellular …, 2020 - Wiley Online Library
In recent decades, mesenchymal stromal cells (MSCs) biomedical utilizing has attracted
worldwide growing attention. After the first report of the human MSCs obtaining from the …

Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential

N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells that are emerging as the most
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …

[HTML][HTML] Multiplicity of mesenchymal stromal cells: finding the right route to therapy

A Wilson, M Hodgson-Garms, JE Frith… - Frontiers in …, 2019 - frontiersin.org
Over the last decade, the acceleration in the clinical use of mesenchymal stromal cells
(MSCs) has been nothing short of spectacular. Perhaps most surprising is how little we know …