Epithelial cell dysfunction has emerged as a central component of the pathophysiology of
diffuse parenchymal diseases including idiopathic pulmonary fibrosis (IPF). Alveolar type 2 …

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
with unknown etiology in which gradual fibrotic scarring of the lungs leads to usual interstitial …

Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic
pulmonary fibrosis (IPF), inhalational, environmental, or occupational exposures in …

Idiopathic pulmonary fibrosis (IPF) is a life-threatening condition, with a median survival of<
3 yrs. The pathophysiology is not fully understood, but chronic injury of alveolar epithelial …

Dating back nearly 35 years ago to the Witschi hypothesis, epithelial cell dysfunction and
abnormal wound healing have reemerged as central concepts in the pathophysiology of …

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive dyspnea, interstitial
infiltrates in lung parenchyma and restriction on pulmonary function testing. IPF is the most …

The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …

Idiopathic pulmonary fibrosis is a disease of older adults leading to progressive dyspnea
and reduced exercise capacity, typically resulting in death within 3-5years of diagnosis …

Idiopathic pulmonary fibrosis (IPF), also termed cryptogenic fibrosing alveolitis, is a
clinicopathological syndrome characterised by cough, exertional dyspneoa, basilar crackles …