[HTML][HTML] Cord-blood-derived professional antigen-presenting cells: Functions and applications in current and prospective cell therapies

S Cunningham, H Hackstein - International Journal of Molecular Sciences, 2021 - mdpi.com
Human umbilical cord blood (UCB) represents a valuable source of hematopoietic stem
cells, particularly for patients lacking a matching donor. UCB provides practical advantages …

Functional Heterogeneity of Umbilical Cord Blood Monocyte-Derived Dendritic Cells

P Schweiger, L Hamann, J Strobel… - The Journal of …, 2024 - journals.aai.org
Human umbilical cord blood (UCB) represents a unique resource for hematopoietic stem
cell transplantation for children and patients lacking suitable donors. UCB harbors a diverse …

Immune regulatory cells in umbilical cord blood and their potential roles in transplantation tolerance

YJ Kim, HE Broxmeyer - Critical reviews in oncology/hematology, 2011 - Elsevier
Umbilical cord blood (UCB) is a source of primitive hematopoietic stem (HSC) and
progenitor cells, that served as an alternative to bone marrow (BM) for effective …

Immunological and regenerative properties of cord blood stem cells

R Francese, P Fiorina - Clinical immunology, 2010 - Elsevier
Cord blood stem cells (CB-SCs) have shown impressive immunological and regenerative
capabilities. In this review, we intend to review the state-of-the-art knowledge on CB-SCs …

[HTML][HTML] Transplantation of umbilical cord blood–derived cells for novel indications in regenerative therapy or immune modulation: a scoping review of clinical studies

MAJ Iafolla, J Tay, DS Allan - Biology of Blood and Marrow Transplantation, 2014 - Elsevier
Although used mainly for transplantation of hematopoietic stem cells in the treatment of
blood disorders, umbilical cord blood (UCB)-based therapies are now being used …

[HTML][HTML] Umbilical cord blood derived cellular therapy: advances in clinical development

J Wang, L Metheny - Frontiers in Oncology, 2023 - frontiersin.org
While cord blood (CB) is primarily utilized in allogeneic hematopoietic cell transplantation
(HCT), the development of novel cell therapy products from CB is a growing and developing …

Therapeutic perspectives for the clinical application of umbilical cord hematopoietic and mesenchymal stem cells: overcoming complications arising after allogeneic …

G Gudauskaitė, I Kairienė, T Ivaškienė… - Cell Biology and …, 2022 - Springer
This review focuses on the therapeutic features of umbilical cord blood (UCB) cells as a
source for allogeneic hematopoietic stem cell transplantation (aHSCT) in adult and child …

[HTML][HTML] Regenerative therapy and immune modulation using umbilical cord blood–derived cells

P Damien, DS Allan - Biology of blood and marrow transplantation, 2015 - Elsevier
Since the first cord blood transplantation in 1988, umbilical cord blood has become an
important option as a source of cells for hematopoietic transplantation. Beyond its role in …

[HTML][HTML] Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells

S Um, J Ha, SJ Choi, W Oh, HJ Jin - World journal of stem cells, 2020 - ncbi.nlm.nih.gov
Umbilical cord blood (UCB) is a primitive and abundant source of mesenchymal stem cells
(MSCs). UCB-derived MSCs have a broad and efficient therapeutic capacity to treat various …

Umbilical cord blood immunology—relevance to stem cell transplantation

SJ Lin, DC Yan, YC Lee, HS Hsiao, PT Lee… - Clinical reviews in …, 2012 - Springer
Because of its easier accessibility and less severe graft-versus-host disease, umbilical cord
blood (UCB) has been increasingly used as an alternative to bone marrow for hematopoietic …