The use of blood for normothermic and subnormothermic kidney preservation hinders the
translation of these approaches and promising therapeutics. This study evaluates whether …

Cold preservation is the standard of care for renal grafts. However, research on alternatives
like perfusion at higher temperatures and supplementing preservation solutions with …

Renal transplantation is the preferred treatment for end-stage renal disease. Currently, there
is a large gap between the supply and demand for transplantable kidneys. The use of sub …

We previously reported that normothermic ex vivo kidney perfusion (NEVKP) is superior in
terms of organ protection compared to static cold storage (SCS), which is still the standard …

Introduction The current methods of preserving donor kidneys in nonoxygenated cold
conditions minimally protect the kidney against ischemia-reperfusion injury (IRI), a major …

Background. The optimal method of oxygen delivery to donor kidneys during ex vivo
machine perfusion has not been established. We have recently reported the beneficial …

Background Normothermic perfusion (NP) has the potential to improve metabolic support
and maintain the viability of ischaemically damaged organs. This study investigated the …

Aim: The scarcity of kidneys for transplantation impels an expansion of the donor source to
include the use of organs from Maastricht II and Maastricht I non heart-beating donors. The …

Static cold storage (SCS) and hypothermic machine perfusion (HMP) are currently standard
methods for renal grafts clinical preservation. Both methods are predominantly implemented …

BACKGROUND: The initial flush of an organ is important to remove any cellular components
from the microcirculation before storage. The aim of this study was to assess graft function …