Early use of antibiotics is associated with a lower incidence of necrotizing enterocolitis in preterm, very low birth weight infants: the NEOMUNE-NeoNutriNet cohort …

Y Li, RL Shen, AI Ayede, J Berrington… - The Journal of …, 2020 - Elsevier
Objective To determine whether commencement of antibiotics within 3 postnatal days in
preterm, very low birth weight (VLBW;≤ 1500 g) infants is associated with the development …

Antibiotic exposure and development of necrotizing enterocolitis in very preterm neonates

R Esmaeilizand, PS Shah, M Seshia… - Paediatrics & Child …, 2018 - academic.oup.com
Objective To examine the association between the duration of antibiotic exposure and
development of stage 2 or 3 necrotizing enterocolitis (NEC) in very preterm neonates. Study …

Broad-spectrum antibiotic plus metronidazole may not prevent the deterioration of necrotizing enterocolitis from stage II to III in full-term and near-term infants: a …

LJ Luo, X Li, KD Yang, JY Lu, LQ Li - Medicine, 2015 - journals.lww.com
Necrotizing enterocolitis (NEC) is the most common and frequently dangerous neonatal
gastrointestinal disease. Studies have shown broad-spectrum antibiotics plus anaerobic …

Early antibiotics and risk for necrotizing enterocolitis in premature infants: A narrative review

A Cuna, MJ Morowitz, V Sampath - Frontiers in Pediatrics, 2023 - frontiersin.org
While prompt initiation of antibiotics at birth due to concerns for early onset sepsis is
common, it often leads to many preterm infants being exposed to treatment despite negative …

Are antibiotics a risk factor for the development of necrotizing enterocolitis—case-control retrospective study

AA Raba, A O'Sullivan, J Semberova, A Martin… - European Journal of …, 2019 - Springer
Previous studies have identified numerous risk factors associated with necrotizing
enterocolitis (NEC) in very low birth weight (VLBW; birth weight less than 1500 g) infants …

Prolonged antibiotic therapy increased necrotizing enterocolitis in very low birth weight infants without culture-proven sepsis

K Zhu, H Gao, L Yuan, L Wang, F Deng - Frontiers in Pediatrics, 2022 - frontiersin.org
Objectives We aimed to identify the factors associated with necrotizing enterocolitis (NEC)
and to assess the associations of the initial empirical antibiotic therapy (IEAT) duration and …

Pathogenesis of necrotising enterocolitis: The impact of the altered gut microbiota and antibiotic exposure in preterm infants

AA Raba, A O'Sullivan, J Miletin - Acta Paediatrica, 2021 - Wiley Online Library
Necrotising enterocolitis (NEC) is a devastating condition with high morbidity and mortality
seen predominately in preterm infants. Multiple factors are associated with the pathogenesis …

Empirical antibiotic treatment and the risk of necrotizing enterocolitis and death in very low birth weight neonates

EA Abdel Ghany, AA Ali - Annals of Saudi medicine, 2012 - annsaudimed.net
BACKGROUND AND OBJECTIVES: Antibiotics are one of the most overused drugs in the
neonatal unit. Our objective was to assess associations between the duration of the initial …

Risk factors that may predispose premature infants to increased incidence of necrotizing enterocolitis

D Drenckpohl, L Knaub, C Schneider… - ICAN: Infant, Child …, 2010 - journals.sagepub.com
The objective of this study was to determine if there are any common “risk factors” that could
assist clinicians in identifying premature infants who are at greater risk for developing …

Incidence and timing of presentation of necrotizing enterocolitis in preterm infants

WH Yee, AS Soraisham, VS Shah, K Aziz, W Yoon… - …, 2012 - publications.aap.org
OBJECTIVES: To examine the variation in the incidence and to identify the timing of the
presentation of necrotizing enterocolitis (NEC) in a cohort of preterm infants within the …