Double-stranded RNA (dsRNA) has recently been shown to trigger sequence-specific gene
silencing in a wide variety of organisms, including nematodes, plants, trypanosomes, fruit …

The use of double-stranded (ds) RNA to manipulate gene expression is evolving into an
increasingly powerful tool to study gene function in organisms ranging from plants to …

RNA interference is a highly conserved pathway mediating sequence-specific RNA
degradation. In plants, the short RNA intermediates of this pathway can also drive …

Double-stranded RNA can induce the degradation of homologous RNAs in organisms as
diverse as protozoa, animals, plants and fungi, resulting in post-transcriptional gene …

In the early 1990s, attempts to manipulate gene expression by researchers working in three
different fields resulted in unanticipated gene silencing. Rather than ignoring such results …

In plants, double-stranded RNA that is processed to short RNAs≈ 21–24 nt in length can
trigger two types of epigenetic gene silencing. Posttranscriptional gene silencing, which is …

Recent studies of gene silencing in plants have revealed two RNA-mediated epigenetic
processes, RNA-directed RNA degradation and RNA-directed DNA methylation. These …

In plants, double-stranded RNA can silence genes by triggering degradation of homologous
RNA in the cytoplasm and by directing methylation of homologous nuclear DNA sequences …

Double-stranded RNA induces a post-transcriptional gene silencing process, termed RNAi,
in diverse organisms. It is shown here that transcriptional gene silencing accompanied by de …

'RNA silencing'is a highly conserved mechanism leading to suppression of gene expression
through nucleotide sequence‐specific interactions that are mediated by 21–24 nucleotide …