Cryo-focused ion beam milling of frozen-hydrated cells and subsequent cryo-electron
tomography (cryo-ET) has enabled the structural elucidation of macromolecular complexes …

Recent advances have made cryogenic (cryo) electron microscopy a key technique to
achieve near-atomic-resolution structures of biochemically isolated macromolecular …

Cryo-focused ion beam milling of frozen-hydrated cells has recently provided
unprecedented insights into the inner space of cells. In combination with cryo-electron …

Cryo-electron tomography (cryoET) has become a powerful technique at the interface of
structural biology and cell biology, due to its unique ability for imaging cells in their native …

Cryo-electron tomography (cryo-ET) is a revolutionary technique for resolving the structure
of subcellular organelles and macromolecular complexes in their cellular context. However …

Cryo-electron tomography (cryo-ET) has become a powerful approach to study the high-
resolution structure of cellular macromolecular machines in situ. However, the current …

Cryo‐electron tomography (cryo‐ET) provides high‐resolution 3D views into cells pristinely
preserved by vitrification. Recent technical advances such as direct electron detectors, the …

Cryo-electron tomography (CET) is a well-established technique for imaging cellular and
molecular structures at sub-nanometer resolution. As the method is limited to samples that …

Cryo-electron tomography (CET) is ideally suited for bridging the resolution gap between
molecular and cellular structural studies. However, CET is limited to a sample thickness …

Cryogenic electron microscopy and data processing enable the determination of structures
of isolated macromolecules to near-atomic resolution. However, these data do not provide …