[图书][B] Multivariate empirical Bayes models for replicated microarray time course data

YC Tai - 2005 - search.proquest.com
Many important biological events occur in a temporal fashion. Microarray time course
experiments measure gene expression levels dynamically for thousands of genes …

A multivariate empirical Bayes statistic for replicated microarray time course data

YC Tai, TP Speed - The Annals of Statistics, 2006 - JSTOR
In this paper we derive one-and two-sample multivariate empirical Bayes statistics (the MB-
statistics) to rank genes in order of interest from longitudinal replicated developmental …

An improved empirical bayes approach to estimating differential gene expression in microarray time-course data: BETR (Bayesian Estimation of Temporal Regulation)

MJ Aryee, JA Gutiérrez-Pabello, I Kramnik, T Maiti… - BMC …, 2009 - Springer
Background Microarray gene expression time-course experiments provide the opportunity to
observe the evolution of transcriptional programs that cells use to respond to internal and …

Bayesian hierarchical modeling for time course microarray experiments

YY Chi, JG Ibrahim, A Bissahoyo, DW Threadgill - Biometrics, 2007 - academic.oup.com
Time course microarray experiments designed to characterize the dynamic regulation of
gene expression in biological systems are becoming increasingly important. One critical …

Functional Empirical Bayes methods for identifying genes with different time-course expression profiles

F Hong, H Li - 2004 - escholarship.org
Time course studies of gene expression are essential in biomedical research to understand
biological phenomena that evolve in a temporal fashion. Microarray technology makes it …

Hidden Markov models for microarray time course data in multiple biological conditions

M Yuan, C Kendziorski - Journal of the American Statistical …, 2006 - Taylor & Francis
Among the first microarray experiments were those measuring expression over time, and
time course experiments remain common. Most methods to analyze time course data …

On gene ranking using replicated microarray time course data

YC Tai, TP Speed - Biometrics, 2009 - academic.oup.com
Consider the ranking of genes using data from replicated microarray time course
experiments, where there are multiple biological conditions, and the genes of interest are …

Statistical Analysis of Time Course Microarray Data

L Ruan, M Yuan - Handbook of Statistical Bioinformatics, 2011 - Springer
Time course gene expression experiments have proved valuable in a variety of studies.
Their unique data structure and the diversity of tasks often associated with them present new …

BATS: a Bayesian user-friendly software for analyzing time series microarray experiments

C Angelini, L Cutillo, D De Canditiis, M Mutarelli… - BMC …, 2008 - Springer
Background Gene expression levels in a given cell can be influenced by different factors,
namely pharmacological or medical treatments. The response to a given stimulus is usually …

Bayesian models for two-sample time-course microarray experiments

C Angelini, D De Canditiis, M Pensky - Computational Statistics & Data …, 2009 - Elsevier
A truly functional Bayesian method for detecting temporally differentially expressed genes
between two experimental conditions is presented. The method distinguishes between two …