Gout and risk of dementia, Alzheimer's disease or vascular dementia: a meta-epidemiology study

X Li, L Huang, Y Tang, X Hu, C Wen - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Objectives The association between gout and dementia, Alzheimer's disease (AD), or
vascular dementia (VD) is not fully understood. The aim of this meta-analysis was to …

Gout and dementia in the elderly: a cohort study of Medicare claims

JA Singh, JD Cleveland - BMC geriatrics, 2018 - Springer
Background Conflicting data in the literature raise the question whether gout, independent of
its treatment, increases the risk of dementia in the elderly. Our objective was to assess …

Risk of dementia in gout and hyperuricaemia: a meta-analysis of cohort studies

SY Pan, RJ Cheng, ZJ Xia, QP Zhang, Y Liu - BMJ open, 2021 - bmjopen.bmj.com
Objectives Gout, characterised by hyperuricaemia with monosodium urate crystal formation
and inflammation, is the most common inflammatory arthritis in adults. Recent studies have …

Gout and the risk of Alzheimer's disease: a population-based, BMI-matched cohort study

N Lu, M Dubreuil, Y Zhang, T Neogi, SK Rai… - Annals of the …, 2016 - ard.bmj.com
Objective While gout is associated with cardiovascular (CV)-metabolic comorbidities and
their sequelae, the antioxidant effects of uric acid may have neuroprotective benefits. We …

Gout and the risk of dementia: a nationwide population-based cohort study

JY Hong, TY Lan, GJ Tang, CH Tang, TJ Chen… - Arthritis research & …, 2015 - Springer
Introduction Uric acid was proposed to have anti-oxidant property and possible
neuroprotective effects. We examined the association between gout and dementia with …

Gout/hyperuricemia reduces the risk of Alzheimer's disease: A meta‐analysis based on latest evidence

L Wang, Z Tan, FY Wang, WP Wu, JC Wu - Brain and Behavior, 2023 - Wiley Online Library
Objective Previous studies have found the potential role of gout or hyperuricemia in
subsequent development of Alzheimer's disease (AD) but reported inconsistent results. We …

Association between gout and dementia in the elderly: a nationwide population-based cohort study

KH Min, SO Kang, SJ Oh, JM Han, KE Lee - The American Journal of …, 2021 - Elsevier
Objective The data showing the association between gout and dementia are inconsistent.
The objective of this study was to examine whether gout is associated with the risk of …

Longitudinal follow-up study of the association with gout and Alzheimer's disease and Parkinson's disease in Korea

EJ Lee, SY Kim, HG Choi, YH Kim, MJ Kwon, JH Kim… - Scientific Reports, 2023 - nature.com
To date, no clear conclusion on the relationships of gout with the occurrence of typical
neurodegenerative diseases, Alzheimer's disease (AD) and Parkinson's disease (PD), has …

Association Between Use of Anti-gout Preparations and Dementia: Nested Case–Control Nationwide Population-Based Cohort Study

TJ Chuang, YH Wang, JCC Wei, CJ Yeh - Frontiers in Medicine, 2021 - frontiersin.org
Objectives: Gout is the most common form of inflammatory arthritis and was found to be
independently associated with incident dementia in the elderly. However, the associations …

Impact of clinical association between gout and dementia: A nationwide population‐based cohort study in Korea

JH Kim, DH Yim, IA Choi, J Lee, H Park… - Arthritis Care & …, 2023 - Wiley Online Library
Objective Hyperuricemia might have neuroprotective or neurodegenerative effects on
dementia via oxidative stress or inflammatory response regulation. Few studies have …