[HTML][HTML] Nutraceuticals and mitochondrial oxidative stress: bridging the gap in the management of bronchial asthma

VSRR Allam, KR Paudel, G Gupta, SK Singh… - … Science and Pollution …, 2022 - Springer
Asthma is a chronic inflammatory disease primarily characterized by inflammation and
reversible bronchoconstriction. It is currently one of the leading causes of morbidity and …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in asthma: implications for mitochondria-targeted antioxidant therapeutics

PH Reddy - Pharmaceuticals, 2011 - mdpi.com
Asthma is a complex, inflammatory disorder characterized by airflow obstruction of variable
degrees, bronchial hyper-responsiveness, and airway inflammation. Asthma is caused by …

Mitochondrial function in allergic disease

D Iyer, N Mishra, A Agrawal - Current allergy and asthma reports, 2017 - Springer
Abstract Purpose of the Review The connections between allergy, asthma and metabolic
syndrome are becoming increasingly clear. Recent research suggests a unifying …

Mitochondria signaling pathways in allergic asthma

L Qian, E Mehrabi Nasab, SM Athari… - Journal of …, 2022 - journals.sagepub.com
Mitochondria, as the powerhouse organelle of cells, are greatly involved in regulating cell
signaling pathways, including those related to the innate and acquired immune systems …

Airway and systemic oxidant-antioxidant dysregulation in asthma: a possible scenario of oxidants spill over from lung into blood

A Nadeem, N Siddiqui, NO Alharbi… - Pulmonary pharmacology …, 2014 - Elsevier
Asthma is characterized by repeated episodes of airway obstruction and an ongoing cycle of
airway inflammation. Reactive oxygen species (ROS) produced by inflammatory cells in the …

[HTML][HTML] Advance of antioxidants in asthma treatment

LY Zhu, ZH Ni, XM Luo, XB Wang - World Journal of Respirology, 2017 - wjgnet.com
Asthma is an allergic disease, characterized as a recurrent airflow limitation, airway
hyperreactivity, and chronic inflammation, involving a variety of cells and cytokines. Reactive …

Targeting the mitochondria in chronic respiratory diseases

DK Chellappan, KR Paudel, NW Tan, KS Cheong… - Mitochondrion, 2022 - Elsevier
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also
the source of respiratory ATP. Recently published studies have demonstrated that …

Oxidant—antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options

A Nadeem, A Masood… - Therapeutic advances in …, 2008 - journals.sagepub.com
Prevalence of asthma has increased considerably in recent decades throughout the world
especially in developed countries. Airway inflammation is thought to be prime cause for …

Mitochondrial dysfunctions associated with chronic respiratory diseases and their targeted therapies: an update

DK Chellappan, V Dharwal, KR Paudel… - Future Medicinal …, 2021 - Future Science
Mitochondria are autonomous cellular organelles present in most of the eukaryotic cells and
are primarily responsible for cellular metabolism. Their structure essentially consists of four …

[HTML][HTML] Mitochondrial dysfunction in metabolic syndrome and asthma

U Mabalirajan, B Ghosh - Journal of Allergy, 2013 - hindawi.com
Though severe or refractory asthma merely affects less than 10% of asthma population, it
consumes significant health resources and contributes significant morbidity and mortality …