Molecular alterations of low-grade gliomas in young patients: Strategies and platforms for routine evaluation

I Dandapath, R Chakraborty, K Kaur… - Neuro-Oncology …, 2021 - academic.oup.com
In recent years, it has been established that molecular biology of pediatric low-grade
gliomas (PLGGs) is entirely distinct from adults. The majority of the circumscribed pediatric …

[PDF][PDF] 652 Neuro-Oncology Practice

I Dandapath, R Chakraborty, K Kaur, S Mahajan… - Neuro …, 2021 - researchgate.net
In recent years, it has been established that molecular biology of pediatric low-grade
gliomas (PLGGs) is entirely distinct from adults. The majority of the circumscribed pediatric …

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype

G Bergthold, P Bandopadhayay, Y Hoshida… - Neuro …, 2015 - academic.oup.com
Background Pediatric low-grade gliomas (PLGGs), the most frequent pediatric brain tumor,
comprise a heterogeneous group of diseases. Recent genomic analyses suggest that these …

[HTML][HTML] Integrated molecular and clinical analysis of 1,000 pediatric low-grade gliomas

S Ryall, M Zapotocky, K Fukuoka, L Nobre, AG Stucklin… - Cancer cell, 2020 - cell.com
Pediatric low-grade gliomas (pLGG) are frequently driven by genetic alterations in the RAS-
mitogen-activated protein kinase (RAS/MAPK) pathway yet show unexplained variability in …

[HTML][HTML] Pediatric low-grade glioma in the era of molecular diagnostics

S Ryall, U Tabori, C Hawkins - Acta neuropathologica communications, 2020 - Springer
Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas

MA Garcia, DA Solomon, DA Haas-Kogan - Future Oncology, 2016 - Taylor & Francis
The majority of brain tumors arising in children are low-grade gliomas. Although historically
categorized together as pediatric low-grade gliomas (PLGGs), there is significant histologic …

Pediatric glial tumors

AN Viaene, M Santi, C Hawkins - Pediatric and …, 2022 - journals.sagepub.com
Pediatric glial tumors are unique from their adult counterparts. This important distinction is
recognized and incorporated into the World Health Organization classification of central …

Molecular biomarkers in pediatric glial tumors: a needed wind of change

AM Fontebasso, D Bechet… - Current Opinion in …, 2013 - journals.lww.com
Molecular biomarkers in pediatric glial tumors: a needed win... : Current Opinion in Oncology
Molecular biomarkers in pediatric glial tumors: a needed wind of change : Current Opinion in …

[HTML][HTML] Approach to integrating molecular markers for assessment of pediatric gliomas

S Mahajan, MC Sharma, C Sarkar… - International Journal of …, 2021 - journals.lww.com
Recent research has promoted elucidation of the diverse biological processes that occur in
pediatric central nervous system (CNS) tumors. These molecular data are leading to new …

Pediatric low-grade gliomas can be molecularly stratified for risk

RR Yang, A Aibaidula, W Wang, AKY Chan, Z Shi… - Acta …, 2018 - Springer
Pediatric low-grade gliomas (PLGGs) consist of a number of entities with overlapping
histological features. PLGGs have much better prognosis than the adult counterparts, but a …