Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-age women, affecting up to 15% of women in this group, and the most common …

Intra-ovarian local factors regulate the follicular microenvironment in coordination with
gonadotrophins, thus playing a crucial role in ovarian physiology as well as pathological …

Polycystic ovary syndrome (PCOS) is one of the most common gynecological endocrine
disorders, with sporadic ovulation, excessive androgens, and polycystic ovarian changes as …

The endoplasmic reticulum (ER) is the principal organelle responsible for several specific
cellular functions including synthesis and folding of secretory or membrane proteins, lipid …

Recent studies report the involvement of intra-ovarian factors, such as inflammation and
oxidative stress, in the pathophysiology of polycystic ovary syndrome (PCOS), the most …

The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …

Polycystic ovary syndrome (PCOS) is associated with hyperandrogenism and growth arrest
of antral follicles. Previously, we found that endoplasmic reticulum (ER) stress is activated in …

Unfolded or misfolded protein accumulation in the endoplasmic reticulum lumen leads to
endoplasmic reticulum stress (ER stress). Although it is known that ER stress is crucial for …

The endoplasmic reticulum (ER) is the organelle where secretory and membrane proteins
are synthesized and folded. Unfolded proteins that are retained within the ER can cause ER …

Vascular endothelial growth factor A (VEGFA) is crucial for ovarian angiogenesis, but its
excess production induces ovarian hyperstimulation syndrome (OHSS). The aim of this …