Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
Induction of phase 2 detoxication enzymes [eg, glutathione transferases, epoxide hydrolase,
NAD (P) H: quinone reductase, and glucuronosyltransferases] is a powerful strategy for …
NAD (P) H: quinone reductase, and glucuronosyltransferases] is a powerful strategy for …
Broccoli sprouts as inducers of carcinogen-detoxifying enzyme systems: clinical, dietary, and policy implications
M Nestle - Proceedings of the National Academy of …, 1997 - National Acad Sciences
Cancer is the second leading cause of death in the United States; it accounts for nearly one-
fourth of annual deaths (1). Although the rates of some cancers have been declining, rates of …
fourth of annual deaths (1). Although the rates of some cancers have been declining, rates of …
Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the …
M Paolini, P Perocco, D Canistro, L Valgimigli… - …, 2004 - academic.oup.com
The reduced cancer risk that appears to be linked to a diet rich in fruits and vegetables has
fueled the belief that regular intake of isolated phytochemicals could potentially prevent …
fueled the belief that regular intake of isolated phytochemicals could potentially prevent …
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
Consumption of vegetables, especially crucifers, reduces the risk of developing cancer.
Although the mechanisms of this protection are unclear, feeding of vegetables induces …
Although the mechanisms of this protection are unclear, feeding of vegetables induces …
Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile
NV Matusheski, EH Jeffery - Journal of agricultural and food …, 2001 - ACS Publications
Epidemiological and laboratory studies suggest that dietary broccoli may prevent or delay a
variety of cancers. Broccoli and other crucifers contain a relatively unique family of …
variety of cancers. Broccoli and other crucifers contain a relatively unique family of …
Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli.
K Faulkner, R Mithen, G Williamson - Carcinogenesis, 1998 - academic.oup.com
The putative anticarcinogenic activity of Brassica vegetables has been associated with the
presence of certain glucosinolates. 4-Methylsulphinylbutyl isothiocyanate (sulphoraphane) …
presence of certain glucosinolates. 4-Methylsulphinylbutyl isothiocyanate (sulphoraphane) …
Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans
TA Shapiro, JW Fahey, KL Wade, KK Stephenson… - … Biomarkers & Prevention, 2001 - AACR
Broccoli sprouts are a rich source of glucosinolates and isothiocyanates that induce phase 2
detoxication enzymes, boost antioxidant status, and protect animals against chemically …
detoxication enzymes, boost antioxidant status, and protect animals against chemically …
Influence of Temperature and Ontogeny on the Levels of Glucosinolates in Broccoli (Brassica oleracea Var. italica) Sprouts and Their Effect on the Induction of …
FMV Pereira, E Rosa, JW Fahey… - Journal of Agricultural …, 2002 - ACS Publications
Broccoli inflorescences have been recognized as components of healthy diets on the basis
of their high content of fiber, vitamin C, carotenoids, and glucosinolates/isothiocyanates …
of their high content of fiber, vitamin C, carotenoids, and glucosinolates/isothiocyanates …
Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli
D James, S Devaraj, P Bellur, S Lakkanna… - Nutrition …, 2012 - academic.oup.com
Consumption of broccoli has long been considered to play a role in a healthy diet. Broccoli
accumulates significant amounts of the phytonutrient glucoraphanin (4-methylsulfinylbutyl …
accumulates significant amounts of the phytonutrient glucoraphanin (4-methylsulfinylbutyl …
Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli
NV Matusheski, JA Juvik, EH Jeffery - Phytochemistry, 2004 - Elsevier
Sulforaphane, an isothiocyanate from broccoli, is one of the most potent food-derived
anticarcinogens. This compound is not present in the intact vegetable, rather it is formed …
anticarcinogens. This compound is not present in the intact vegetable, rather it is formed …