Purpose We hypothesized that a treatment planning technique that incorporates predicted
lung tumor regression into optimization, predictive treatment planning (PTP), could allow …

Purpose To cross-validate and expand a predictive atlas that can estimate geometric
patterns of lung tumor shrinkage during radiation therapy using data from 2 independent …

PURPOSE: To quantify the differences in doses to target volumes and critical thoracic
structures calculated by traditional homogeneous point–dose prescription and heterogeneity …

Objective. Traditional radiotherapy (RT) treatment planning of non-small cell lung cancer
(NSCLC) relies on population-wide estimates of organ tolerance to minimize excess toxicity …

Purpose: To determine how much the radiation dose to lung tumors could be increased as
the margins used to generate planning target volume (PTV) are reduced. Methods and …

The purpose of this study was to develop metrics to evaluate uncertainties in deformable
dose accumulation for patients with non-small cell lung cancer (NSCLC). Initial treatment …

Purpose: To quantify the potential benefit associated with daily replanning in lung cancer in
terms of normal tissue dose sparing and to characterize the tradeoff between adaptive …

Purpose In this planning study, we studied the benefit of intensity-modulated radiation
therapy (IMRT) with multi-criteria optimization (MCO) in locally advanced non-small cell lung …

BACKGROUND AND PURPOSE: Loco-regional failure after radiotherapy with total doses of
60–70 Gy for non-small cell lung cancer (NSCLC) remains a major clinical problem …

PURPOSE: To analyze dosimetric variables and outcomes after adaptive replanning of
radiation therapy during concurrent high-dose protons and chemotherapy for locally …