The role of peptides as signalling molecules in the nervous system has been studied for
more than 30 years. Neuropeptides and their G-protein-coupled receptors are widely …

This review examines our current understanding of the roles of some of the best known
neuropeptides that have played major roles in our combined research programmes …

The recent development of selective and highly potent nonpeptide antagonists for peptide
receptors has constituted a major breakthrough in the field of neuropeptide research …

The present article provides a brief overview of various aspects on neuropeptides,
emphasizing their multitude and their wide distribution in both the peripheral and central …

The number of neuropeptides and their corresponding receptors has increased steadily over
the last fourty years: initially, peptides were isolated from gut or brain (eg, Substance P …

This textbook is the first to bring together and synthesize the neuropeptide research of the
past decade in such a comprehensive, scholarly manner. In recent years there has been …

In the early 1970's the term" neuropeptide" was used for the first time by David de Wied for
peptides related to peptide hormones but with non-endocrine biological activity in the brain …

We know neuropeptides now for over 40 years as chemical signals in the brain. The
discovery of neuropeptides is founded on groundbreaking research in physiology …

9 inal cord of various mammal&. The first mammalian peptide to be sequenced, substance P
(SP), was extracted in 1970 from the bovine hypothalamus by Chang and Leeman'; more …

Neuropeptide S (NPS) is the last neuropeptide identified via reverse pharmacology
techniques. NPS selectively binds and activates a previous orphan GPCR, now named …