In the pathogenesis of several rheumatic diseases, such as rheumatoid arthritis,
spondyloarthritis, osteoarthritis, osteoporosis, alterations in osteoblast growth, differentiation …

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease in which destruction of
bone in the joints causes major morbidity. Recent research has shed light on the cell and …

This review summarizes the recent advances of osteoimmunology, a new research field that
investigates the interaction of the immune system with the skeleton. Osteoimmunology has …

Structural disturbances of the subchondral bone are a hallmark of osteoarthritis (OA),
including sclerotic changes, cystic lesions, and osteophyte formation. Osteocytes act as …

Rheumatoid arthritis (RA), an autoimmune disease, is characterized by the presence of
symmetric polyarthritis predominantly of the small joints that leads to severe cartilage and …

Rheumatoid arthritis (RA) is an inflammatory disease characterized by a variety of symptoms
and pathologies often presenting with polyarthritis. The primary symptom in the initial stage …

Over the past two decades, the field of osteoimmunology has emerged in response to a
range of evidence demonstrating the reciprocal relationship between the immune system …

Introduction Rheumatoid arthritis (RA), which affects nearly 1% of the world's population, is a
debilitating autoimmune disease. Bone erosion caused by periarticular osteopenia and …

Arthritic diseases cause enormous burdens in terms of pain, crippling, and disability.
Osteoarthritis (OA), the most common form of arthritis, is characterized by a slow progressive …

Chronic synovial inflammation is usually accompanied by bone erosion. Due to resulting
structural damage, bone erosion is a major reason for disability in RA patients. Anti …