Pulsatile GnRH release is essential for normal reproductive function. Kisspeptin secreting
neurons found in the arcuate nucleus, known as KNDy neurons for co-expressing …

Highly sophisticated and synchronized interactions of various cells and hormonal signals
are required to make organisms competent for reproduction. GnRH neurons act as a …

Reproductive function is driven by the hormonal interplay between the gonads and brain–
pituitary axis. Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner …

Accumulating findings during the past decades have demonstrated that the hypothalamic
arcuate kisspeptin neurons are supposed to be responsible for pulsatile release of …

Fertility relies upon pulsatile release of gonadotropin-releasing hormone (GnRH) that drives
pulsatile luteinizing hormone secretion. Kisspeptin (KP) neurons in the arcuate nucleus are …

Gonadotropin-releasing hormone (GnRH) is the final output of the central nervous system
that drives fertility. A characteristic of GnRH secretion is its pulsatility, which is driven by a …

The gonadotropin-releasing hormone (GnRH) pulse is fundamental for mammalian
reproduction: GnRH pulse regimens are needed as therapies for infertile women as …

Kisspeptin (Kiss1) and neurokinin B (NKB) neurocircuits are essential for pubertal
development and fertility. Kisspeptin neurons in the hypothalamic arcuate nucleus …

Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the
physiological menstrual cycle including the release of gonadotrophins to stimulate follicular …

Reproduction is controlled in the brain by a neural network that drives the secretion of
gonadotropin-releasing hormone (GnRH). Various permissive homeostatic signals must be …