Design, synthesis, molecular modeling, and biological evaluation of novel kojic acid derivatives containing bioactive heterocycle moiety as inhibitors of tyrosinase and …
M He, M Fan, W Liu, Y Li, G Wang - Food Chemistry, 2021 - Elsevier
Tyrosinase plays an important role in melanin biosynthesis and enzymatic browning of fresh-
cut fruit and vegetables. To discover potent tyrosinase inhibitors and antibrowning agents, a …
cut fruit and vegetables. To discover potent tyrosinase inhibitors and antibrowning agents, a …
[HTML][HTML] Tyrosinase inhibitory mechanism and anti-browning properties of novel kojic acid derivatives bearing aromatic aldehyde moiety
Z Peng, G Wang, Y He, JJ Wang, Y Zhao - Current Research in Food …, 2023 - Elsevier
Kojic acid-aromatic aldehydes 6a-6m were synthesized and screened for their anti-
tyrosinase activities. These compounds showed potently anti-tyrosinase activity with IC 50 …
tyrosinase activities. These compounds showed potently anti-tyrosinase activity with IC 50 …
Design and synthesis of chalcone derivatives as potent tyrosinase inhibitors and their structural activity relationship
Browning of fruits and vegetables is a serious issue in the food industry, as it damages the
organoleptic properties of the final products. Overproduction of melanin causes aesthetic …
organoleptic properties of the final products. Overproduction of melanin causes aesthetic …
Synthesis and evaluation of the antioxidant and anti-tyrosinase activities of thiazolyl hydrazone derivatives and their application in the anti-browning of fresh-cut potato
Tyrosinase is a key enzyme in the biosynthesis of melanin, which is responsible for the
browning of foods as well as many skin disorders. In order to develop new anti-browning …
browning of foods as well as many skin disorders. In order to develop new anti-browning …
Design, synthesis, in vitro and in silico studies of novel Schiff base derivatives of 2‐hydroxy‐4‐methoxybenzamide as tyrosinase inhibitors
Due to the fact that tyrosinase is responsible for biosynthesis and regulation of melanins and
browning food products, tyrosinase inhibitors can be favorable agents in cosmetics and …
browning food products, tyrosinase inhibitors can be favorable agents in cosmetics and …
Novel kojic acid-1, 2, 4-triazine hybrids as anti-tyrosinase agents: Synthesis, biological evaluation, mode of action, and anti-browning studies
M He, M Fan, W Yang, Z Peng, G Wang - Food Chemistry, 2023 - Elsevier
A class of new kojic acid hybrids (7a-7o) bearing a 1, 2, 4-triazine moiety were prepared,
and their inhibitory activities and mechanism on tyrosinase were investigated. All derivatives …
and their inhibitory activities and mechanism on tyrosinase were investigated. All derivatives …
[HTML][HTML] Synthesis and tyrosinase inhibitory properties of some novel derivatives of kojic acid
Tyrosinase is a multifunctional oxidase that is widely distributed in nature. It is a key enzyme
in melanin biosynthesis and is involved in determining the color of mammalian skin and hair …
in melanin biosynthesis and is involved in determining the color of mammalian skin and hair …
Screening and identification of tyrosinase inhibitors in edible plant materials by on-line UPLC-enzyme reactor coupled with UHPLC-FTMS
X Fang, L Dai, TM Ding, Y Zhu, JF Zan, LL Chen… - Food Chemistry, 2023 - Elsevier
Tyrosinase plays a primary role in melanin biosynthesis and enzymatic browning of freshly
cut fruits and vegetables. Herein, an on-line ultraperformance liquid chromatography diode …
cut fruits and vegetables. Herein, an on-line ultraperformance liquid chromatography diode …
Synthesis, Anti-Tyrosinase Activity, and Spectroscopic Inhibition Mechanism of Cinnamic Acid–Eugenol Esters
J Li, X Min, X Zheng, S Wang, X Xu, J Peng - Molecules, 2023 - mdpi.com
Tyrosinase plays crucial roles in mediating the production of melanin pigment; thus, its
inhibitors could be useful in preventing melanin-related diseases. To find potential …
inhibitors could be useful in preventing melanin-related diseases. To find potential …
Novel morpholine containing cinnamoyl amides as potent tyrosinase inhibitors
Tyrosinase enzyme plays a crucial role in melanin biosynthesis and enzymatic browning
process of vegetables and fruits. Hence, tyrosinase inhibitors are important in the fields of …
process of vegetables and fruits. Hence, tyrosinase inhibitors are important in the fields of …
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