In vitro and in vivo anticancer activity of copper bis (thiosemicarbazone) complexes

D Palanimuthu, SV Shinde… - Journal of medicinal …, 2013 - ACS Publications
Neutral and cationic copper bis (thiosemicarbazone) complexes bearing methyl, phenyl, and
hydrogen, on the diketo-backbone of the ligand have been synthesized. All of them were …

Synthesis, characterization, and in vitro anticancer activity of copper and zinc bis (thiosemicarbazone) complexes

R Anjum, D Palanimuthu, DS Kalinowski… - Inorganic …, 2019 - ACS Publications
A series of eight bis (thiosemicarbazone) ligands and 16 of their respective copper (II) and
zinc (II) complexes containing a combination of hydrogen, methyl, pyridyl, phenyl, and/or …

Synthesis, characterization, and biological activity of hybrid thiosemicarbazone–alkylthiocarbamate metal complexes

SA Andres, K Bajaj, NS Vishnosky… - Inorganic …, 2020 - ACS Publications
A series of hybrid ligands (H 2 L 1–H 2 L 3) derived from 4-methyl-3-thiosemicarbazide and
hydrazinecarbothioic acid O-alkyl esters were synthesized and characterized by NMR. The …

Zinc (II) complexes derived from pyridine-2-carbaldehyde thiosemicarbazone and (1E)-1-pyridin-2-ylethan-1-one thiosemicarbazone. Synthesis, crystal structures and …

D Kovala-Demertzi, PN Yadav, J Wiecek… - Journal of Inorganic …, 2006 - Elsevier
The complexes [ZnCl2 (HFoTsc)· H2O],[Zn (FoTsc) 2],[ZnCl2 (HAcTsc)· H2O] and [Zn (AcTsc)
2], where HFoTsc and HAcTsc is pyridine-2-carbaldehyde thiosemicarbazone and (1E)-1 …

In vitro and in vivo anticancer activity of tridentate thiosemicarbazone copper complexes: Unravelling an unexplored pharmacological target

M Carcelli, M Tegoni, J Bartoli, C Marzano… - European Journal of …, 2020 - Elsevier
Certain metal complexes can have a great antitumor activity, as the use of cisplatin in
therapy has been demonstrating for the past fifty years. Copper complexes, in particular …

Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu (I/II) complexes of thiosemicarbazone: special emphasis on their interactions with DNA

A Chakraborty, SP Dash, AK Panda, R Acharyya… - Dalton …, 2015 - pubs.rsc.org
4-(pX-phenyl) thiosemicarbazone of napthaldehyde {where X= Cl (HL1) and X= Br (HL2)},
thiosemicarbazone of quinoline-2-carbaldehyde (HL3) and 4-(p-fluorophenyl) …

Synthesis, characterization and biological activity of two new polymeric copper (II) complexes with α-ketoglutaric acid thiosemicarbazone

MB Ferrari, F Bisceglie, GG Fava, G Pelosi… - Journal of inorganic …, 2002 - Elsevier
In this paper we describe the synthesis of new copper complexes with α-ketoglutaric acid
thiosemicarbazone. The crystal structures of the two compounds:[Cu (H2ct) Cl] n [{Cu (H2ct) …

Synthesis, characterization and biological activity of copper complexes with pyridoxal thiosemicarbazone derivatives. X-ray crystal structure of three dimeric …

MB Ferrari, F Bisceglie, G Pelosi, P Tarasconi… - Journal of inorganic …, 2004 - Elsevier
A dimeric copper complex of the unsubstituted pyridoxal thiosemicarbazone (H2L),[{Cu
(HL)(OH2)} 2] Cl2· 2H2O, previously tested on Friend murine cell lines has been recently …

Synthesis and crystal structure of new monometallic and bimetallic copper (II) complexes with N-substituted isatin thiosemicarbazone ligands: Effects of the complexes …

M Muralisankar, S Sujith, NSP Bhuvanesh… - Polyhedron, 2016 - Elsevier
A novel series of N-substituted isatin thiosemicarbazone ligands (L1–L3) and their copper
(II) complexes [Cu (II)(ITSC)] were synthesized and characterized by elemental analyses …

Antiproliferative activity of cationic and neutral thiosemicarbazone copper (II) complexes

MM Subarkhan, RN Prabhu, RR Kumar, R Ramesh - RSC advances, 2016 - pubs.rsc.org
The copper (II) complexes,[Cu (tscpy)(MeOH)](Cl)(1),[CuCl (mtscpy)](2) and [CuCl
(ptscpy)](3)(where, Htscpy= pyridoxal thiosemicarbazone, Hmtscpy= pyridoxal N4-methyl …