The cell cycle pattern of the pathogenic basidiomycetous yeast Cryptococcus neoformans
differs from that of the ascomycetous budding yeast Saccharomyces cerevisiae. To clarify …

We have previously reported that only a single Cdk1-related G1 and G1/S cyclin homologue
was found in the genome sequence of the pathogenic basidiomycetous yeast Cryptococcus …

A partial cDNA fragment of the Cryptococcus neoformans homologue of the main cell cycle
control gene CDC28/cdc2 was isolated using degenerate primer RT-PCR. A subsequent …

Major transitions in the eukaryotic cell cycle are regulated by the cyclin-dependent protein
kinases (CDK). In particular, the G2/M transition is initiated by the activity of a complex …

Cyclin-dependent kinases (CDKs) are key regulators of eukaryotic cell cycle progression.
The cyclin subunit activates the CDK and also imparts to the complex, at least in some …

The fungal pathogen Cryptococcus neoformans has several virulence factors, among which
the most important is a polysaccharide capsule. The size of the capsule is variable and can …

Cell cycle progression in the budding yeast Saccharomyces cerevisiae is controlled by the
Cdc28 protein kinase, which is sequentially activated by different sets of cyclins. Previous …

The pathogenic yeast Cryptococcus neoformans causes fungal meningitis in immune-
compromised patients. Cell proliferation in the budding yeast form is required for C …

In the budding yeast Saccharomyces cerevisiae, progress of the cell cycle beyond the major
control point in G1 phase, termed START, requires activation of the evolutionarily conserved …

Crk1, a Cdc2-related protein kinase from the human pathogenic fungus Candida albicans,
plays an important role in hyphal development and virulence. To address its regulatory …